6pbc

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Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations

Structural highlights

6pbc is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.46Å
Ligands:CA, NA
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

G3V845_RAT Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.[PIRNR:PIRNR000952]

See Also

Contents


PDB ID 6pbc

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