6wi2

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Structure of human mitochondrial complex Nfs1-ISCU2-ISD11 with E.coli ACP1 at 1.95 A resolution (NIAU)2. N-terminal mutation of ISCU2 (L35) traps Nfs1 Cys loop in the active site of ISCU2 without metal present.

Structural highlights

6wi2 is a 4 chain structure with sequence from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.95Å
Ligands:1PE, 8Q1, EDO, EDT, ETE, GOL, MES, PEG, PG4, PGE, PLP
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ACP_ECOLI Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217]

See Also

Contents


PDB ID 6wi2

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OCA

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