6zhu

From Proteopedia

Yeast Uba1 in complex with Ubc3 and ATP

Structural highlights

6zhu is a 8 chain structure with sequence from Saccharomyces cerevisiae and Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.18Å
Ligands:	ATP, MG
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UBC3_YEAST Catalyzes the covalent attachment of ubiquitin to other proteins. Capable, in vitro, to ubiquitinate histone H2A. Mediates the initiation of DNA replication (transition of G1 to S phase in cell cycle). Essential component of the E3 ubiquitin ligase complex SCF (SKP1-CUL1-F-box protein), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the regulation of methionine biosynthesis genes and in the degradation of CDC6 together with CDC4 and CDC53.

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PDB ID 6zhu

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Categories: Large Structures | Saccharomyces cerevisiae | Saccharomyces cerevisiae S288C | Misra M | Schindelin H

6zhu

From Proteopedia

Yeast Uba1 in complex with Ubc3 and ATP

Structural highlights

Function

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