7agg

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HAd7 knob in complex with 2 EC2-EC3 modules of DSG-2

Structural highlights

7agg is a 5 chain structure with sequence from Homo sapiens and Human adenovirus 7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SPIKE_ADE07 Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface.[1]

See Also

References

  1. ↑ Miyazawa N, Crystal RG, Leopold PL. Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein. J Virol. 2001 Feb;75(3):1387-400. PMID:11152512 doi:10.1128/JVI.75.3.1387-1400.2001

Contents


PDB ID 7agg

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OCA

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