7jic

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Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment

Structural highlights

7jic is a 4 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

CD19_HUMAN Common variable immunodeficiency. The disease is caused by mutations affecting the gene represented in this entry.

Function

CD19_HUMAN Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

See Also

Contents


PDB ID 7jic

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OCA

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