7jug

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C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with Man-alpha1-6Man

Structural highlights

7jug is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.4Å
Ligands:CA, MAN
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MRC1_HUMAN Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.

Contents


PDB ID 7jug

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OCA

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