7l70

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The eukaryotic translation initiation factor 2B from Homo sapiens in its apo form

Structural highlights

7l70 is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

EI2BA_HUMAN Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.

Function

EI2BA_HUMAN Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

See Also

Contents


PDB ID 7l70

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OCA

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