Structural highlights
7q4i is a 4 chain structure with sequence from Drosophila melanogaster and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Method: | X-ray diffraction, Resolution 2.4Å |
| Ligands: | , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
C1GLT_DROME Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.[1]
References
- ↑ Lin YR, Reddy BV, Irvine KD. Requirement for a core 1 galactosyltransferase in the Drosophila nervous system. Dev Dyn. 2008 Dec;237(12):3703-14. doi: 10.1002/dvdy.21775. PMID:18985719 doi:http://dx.doi.org/10.1002/dvdy.21775
