7uhg

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Human L-type voltage-gated calcium channel Cav1.3 at 3.0 Angstrom resolution

Structural highlights

7uhg is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3Å
Ligands:3PE, CA, CLR, NAG
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CACB3_HUMAN Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:8119293). Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity). Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity).[UniProtKB:P54287][UniProtKB:Q9MZL3][1]

See Also

References

  1. Collin T, Lory P, Taviaux S, Courtieu C, Guilbault P, Berta P, Nargeot J. Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit. Eur J Biochem. 1994 Feb 15;220(1):257-62. PMID:8119293 doi:10.1111/j.1432-1033.1994.tb18621.x

Contents


PDB ID 7uhg

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