8che

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TLT-1 binding Fab of the bispecific antibody HMB-001 in complex with the TLT-1 stalk peptide

Structural highlights

8che is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.49Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TRML1_HUMAN Cell surface receptor that may play a role in the innate and adaptive immune response.[1]

References

  1. ↑ Barrow AD, Astoul E, Floto A, Brooke G, Relou IA, Jennings NS, Smith KG, Ouwehand W, Farndale RW, Alexander DR, Trowsdale J. Cutting edge: TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2. J Immunol. 2004 May 15;172(10):5838-42. PMID:15128762

Contents


PDB ID 8che

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OCA

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