8fwl

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Crystal structure of Australian bat lyssavirus nucleoprotein in complex with phosphoprotein chaperone

Structural highlights

8fwl is a 1 chain structure with sequence from Lyssavirus australis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.19Å
Ligands:PEG
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q9YZ24_9RHAB A0A7M4C440_9RHAB Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus.[RuleBase:RU004918]

See Also

Contents


PDB ID 8fwl

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OCA

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