8gcl

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Cryo-EM structure of hAQP2 in DDM

Structural highlights

8gcl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.89Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

AQP2_HUMAN Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry.

Function

AQP2_HUMAN Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

Contents


PDB ID 8gcl

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OCA

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