Structural highlights
Function
VIPP1_NOSP7 A membrane remodeling protein capable of forming rings and/or filaments on membranes, which then curve and tubulate the bilayer (Probable) (PubMed:34166615). Rings will form on liposomes, altering their positive curvature so the lipid bilayer is remodeled into a negative curve as the membrane enters the ring (PubMed:34166615). Ring stacks of varying lengths can be seen joining isolated liposomes (PubMed:34166615). A lipid monolayer can be drawn into the center of the rings (PubMed:34166615). Required for thylakoid formation (By similarity).[UniProtKB:Q55707][1] [2]
References
- ↑ Liu J, Tassinari M, Souza DP, Naskar S, Noel JK, Bohuszewicz O, Buck M, Williams TA, Baum B, Low HH. Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily. Cell. 2021 Jul 8;184(14):3660-3673.e18. doi: 10.1016/j.cell.2021.05.041. Epub, 2021 Jun 23. PMID:34166615 doi:http://dx.doi.org/10.1016/j.cell.2021.05.041
- ↑ Liu J, Tassinari M, Souza DP, Naskar S, Noel JK, Bohuszewicz O, Buck M, Williams TA, Baum B, Low HH. Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily. Cell. 2021 Jul 8;184(14):3660-3673.e18. doi: 10.1016/j.cell.2021.05.041. Epub, 2021 Jun 23. PMID:34166615 doi:http://dx.doi.org/10.1016/j.cell.2021.05.041