9f6f

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Human DNA polymerase epsilon bound to DNA and PCNA (closed conformation)

Structural highlights

9f6f is a 6 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.75Å
Ligands:2DA, DDS, SF4
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

DPOE1_HUMAN Facial dysmorphism - immunodeficiency - livedo - short stature. Disease susceptibility is associated with variations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.

Function

DPOE1_HUMAN Participates in DNA repair and in chromosomal DNA replication.

Contents


PDB ID 9f6f

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OCA

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