9lhm | pdb_00009lhm
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hPAC structure in the presence of MbCD
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Structural highlights
FunctionPACC1_HUMAN Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH (PubMed:31023925, PubMed:31318332). Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling (PubMed:31023925, PubMed:31318332).[1] [2] References
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This page was last modified 05:44, 30 July 2025.