Flurbiprofen

From Proteopedia

(Redirected from Ansaid)

Flurbiprofen is a member of the phenylalkanoic acid derivative family of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or dental pain. Side effects are analogous to those of ibuprofen. See also Flurbiprofen.

NSAIDs such as Flurbiprofen work by inhibiting the cyclooxygenase (COX) enzymes, which convert arachidonic acid to prostaglandin H2 (PGH2). PGH2, in turn, is converted by other enzymes to several other prostaglandins (which are mediators of pain, inflammation, and fever) and to thromboxane A2 (which stimulates platelet aggregation, leading to the formation of blood clots).

CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A NON-SELECTIVE INHIBITOR, FLURBIPROFEN (3pgh).

Flurbiprofen binding site.

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3394

Marvin 12300703363D

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Flurbiprofen

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References

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

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Flurbiprofen

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