Apurinic-Apyrimidinic Endonuclease

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Zebrafish APE1 trimer interacting with Pb+2 ions. 2o3c

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References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Masood, Z.H. 2000. Functional characterization of APE1 varients identified in the human population. Nucleic Acid Research 28: 3871-3879
  2. Guikema JE, Linehan EK, Esa N, Tsuchimoto D, Nakabeppu Y, Woodland RT, Schrader CE. Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells. J Immunol. 2014 Jul 15;193(2):931-9. doi: 10.4049/jimmunol.1400002. Epub 2014 Jun, 16. PMID:24935922 doi:http://dx.doi.org/10.4049/jimmunol.1400002
  3. Daley JM, Zakaria C, Ramotar D. The endonuclease IV family of apurinic/apyrimidinic endonucleases. Mutat Res. 2010 Dec;705(3):217-27. doi: 10.1016/j.mrrev.2010.07.003. Epub 2010, Aug 3. PMID:20667510 doi:http://dx.doi.org/10.1016/j.mrrev.2010.07.003
  4. 4.0 4.1 Barnes, T., et al. 2009. Identification of Apurinic/apyrimidinic endoribonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA in vitro. Nucleic Acid Research 37: 3946-3958
  5. 5.0 5.1 5.2 Ando, K. et al. 2008. A new APE1/Ref-1-dependent pathway leading to reduction of NF-kB and AP-1, and activation of their DNA binding activity. Nucleic Acid research 36(13): 4327-4336.
  6. 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 6.8 6.9 Mol,C.D. et al. 2000. DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination. Nature 403:451-456.

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