Argonaute 3D structures

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3D Structures of Argonaute

Updated on 11-November-2024

Argonaute 1

1si2, 1si3 – hAGO1 PAZ domain + RNA - human

4kre, 4krf, 4kxt - hAGO1 + RNA

5w6v - hAGO1 + RNA + protein GW1

1r4k – DmAGO1 PAZ domain – Drosophila melanogaster

4g0p, 4g0x, 3vna – AtAGO1 MID domain – Arabidopsis thaliana

3vnb – AtAGO1 MID domain (mutant)

4g0q, 4g0y, 4g0z – AtAGO1 MID domain + nucleotide

8r3z - AGO1 + RNA – Candidatus harpoatesius – Cryo EM

Argonaute 2; Domains – PAZ 227-352; MID 439-575

3luc, 3luk – hAGO2 MID domain

3lud, 3lug, 3luh, 3luj, 3qx8, 3qx9, 7c6b, 7d7u, 9bf0, 9bf2 – hAGO2 MID domain + nucleotide

9bez – hAGO2 MID domain + RNA

8thq – hAGO2 PAZ domain + RNA

4f3t, 4ola, 4olb, 4w5o, 5ki6, 5t7b, 6ra4, 8d6j, 8d71 – hAGO2 + RNA

4w5n, 4w5q, 4w5r, 4w5t, 4z4i, 4z4h, 4z4g, 4z4f, 4z4e, 4z4d, 4z4c, 4ola, 5js1, 5js2, 5wea, 6cbd, 6mdz, 6mfn, 6mfr, 6n4o, 6nit – hAGO2 (mutant) + RNA

4olb - hAGO2 (mutant) + RNA + tryptophan

4f3t, 4w5o, 5t7b – hAGO2 + RNA

7ki3 – hAGO2 + RNA + Hepatitis C RNA

1r6z – DmAGO2 PAZ domain/MBP

1vyn – DmAGO2 PAZ domain - NMR

1t2r, 1t2s – DmAGO2 PAZ domain + RNA - NMR

3mj0 – DmAGO2 PAZ domain + RNA

4g0m, 4g0o – AtAGO2 MID domain

Argonaute 3

5vm9, 8vaj – hAGO3 + RNA

Argonaute 4

6oon – hAGO4 + RNA

Argonaute 10

7sva, 7swf, 7swq – AtAGO10 + RNA – Cryo EM

Argonaute

1u04, 1z25, 1z26 – PfAGO (mutant) – Pyrococcus furiosus

8jpx – PfAGO + DNA – Cryo EM

2f8s, 2f8t – AaAGO + RNA – Aquifex aeolicus

2f8t, 2nub – AaAGO

3da5 – TtAGO – Thermococcus thioreducens

8jsi, 8wd8 – TtAGO + DNA – Cryo EM

8j84, 8u7b – AGO + TIR-APAZ – Thermoflavidium thermophilus

8qlo – AGO + TIR-APAZ – Bacillales bacterium

3dlb, 3dlh, 3f73, 3hm9, 3hvr, 3hxm, 4n41, 4n47, 4n76, 4nca, 4ncb, 5gq9 – TtAGO + DNA – Thermus thermophilus

3hjf, 3hk2, 3ho1 – TtAGO (mutant) + DNA

5i4a – MpAGO + RNA – Marinitoga piezophila

5ux0 – MpAGO (mutant) + RNA + DNA

5g5s – MjAGO – Methanocaldococcus jannaschii

5g5t – MjAGO + DNA

6qzk – AGO (mutant) + DNA – Clostridium butyricum

7r8f, 7r8k – PlAGO – Pseudooceanicola lipolyticus

7r8g, 7r8h, 7r8i, 7r8j – PlAGO + DNA

8ok9 – AGO + AGO-N + DNA – Archaeoglobus fulgidus

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Michal Harel

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Argonaute 3D structures

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3D Structures of Argonaute

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