Aromatic amine dehydrogenase

From Proteopedia

Function Aromatic amine dehydrogenase (AADH) catalyzes the conversion of primary aromatic amine and acceptor to aldehyde and reduced acceptor. The acceptor co-factor is tryptophan tryptophylquinone (TTQ).[1] Structural highlights AADH structure consists of 2 large and 2 small subunits with the co-factor TTQ attached covalently to the small subunit.[2] 3D structures of aromatic amine dehydrogenase Aromatic amine dehydrogenase 3D structures

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References

1. ↑ Govindaraj S, Eisenstein E, Jones LH, Sanders-Loehr J, Chistoserdov AY, Davidson VL, Edwards SL. Aromatic amine dehydrogenase, a second tryptophan tryptophylquinone enzyme. J Bacteriol. 1994 May;176(10):2922-9. PMID:8188594
2. ↑ Roujeinikova A, Hothi P, Masgrau L, Sutcliffe MJ, Scrutton NS, Leys D. New insights into the reductive half-reaction mechanism of aromatic amine dehydrogenase revealed by reaction with carbinolamine substrates. J Biol Chem. 2007 Aug 17;282(33):23766-77. Epub 2007 May 1. PMID:17475620 doi:10.1074/jbc.M700677200