Beta-lactam antibiotics

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β-lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a beta-lactam ring in their chemical structure. This includes penicillin derivatives (penams), cephalosporins and cephamycins (cephems), monobactams, carbapenems and carbacephems. Most β-lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organism and are the most widely used group of antibiotics. See also Beta-lactam antibiotics.

D-alanyl-D-alanine carboxipeptidase transpeptidase complex with cephalothin (PDB code 1ceg)

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References

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Alexander Berchansky

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