Chitinase-3-like protein

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Glycosylated chitinase-3-like protein 1 tetramer complex with chitin tetramer and sulfate, (PDB code 1hjv)

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References

  1. Houston DR, Recklies AD, Krupa JC, van Aalten DM. Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes. J Biol Chem. 2003 Aug 8;278(32):30206-12. Epub 2003 May 29. PMID:12775711 doi:10.1074/jbc.M303371200
  2. Hinsinger G, Galeotti N, Nabholz N, Urbach S, Rigau V, Demattei C, Lehmann S, Camu W, Labauge P, Castelnovo G, Brassat D, Loussouarn D, Salou M, Laplaud D, Casez O, Bockaert J, Marin P, Thouvenot E. Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis. Mult Scler. 2015 Sep;21(10):1251-61. doi: 10.1177/1352458514561906. Epub 2015 Feb, 19. PMID:25698171 doi:http://dx.doi.org/10.1177/1352458514561906

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