DNA ligase 3D structures

From Proteopedia

Jump to: navigation, search

proteopedia link proteopedia link

3D Structures of DNA ligase

Updated on 31-January-2023

ATP-dependent LigD

3p4h, 3ta5, 3ta7 – LigD N-terminal – Candidatus korarchaeum cryptofilum

3gde – LigD – Archaeoglobus fulgidus

2hiv – SsLigD – Sulfolobus solfataricus

2hix - SsLigD + ATP

2cfm - LigD + AMP – Pyrococcus furiosus

2fao - PaLigD polymerase domain – Pseudomonas aeruginosa

2faq, 2far - PaLigD polymerase domain + ATP + Mn

1a0i – LigD (mutant) + ATP – Bacteriophage T7

4eq5 – LigD + AMP – Thermococcus sibiricus

4d05 – LigD + AMP - Psychromonas

6nhx, 6nhz – MtLigD D + ATP - Mycobacterium tuberculosis

2iru – MtLigD D polymerase domain 1-300

2irx, 2iry – MtLigD D polymerase domain + GTP

3pky – MtLigD D polymerase domain + DNA + UTP

2r9l, 4mky – MtLigD D polymerase domain + DNA

6rar, 6ras, 6rce - PmLigD + CMP + AMP – Prochlorococcus marinus

6rau - PmLigD + AMP

7obn - LigD + AMP + CMP + DNA – Burkholderia pseudomallei<br />

NAD+-dependent LigD

3jsl, 3jsn - SaLigD adenylation domain – Staphylococcus aureus

4cc5, 4cc6, 5fpo, 5fpr – SaLigD adenylation domain + inhibitor

3ba8, 3ba9, 3baa, 3bab, 3bac, 4eeq, 4efb, 4efe, 4lh6, 4lh7 - EfLigD adenylation domain + NMN + inhibitor – Enterococcus faecalis

1ta8, 1tae - EfLigD adenylation domain

1zau - MtLigD adenylation domain

3sgi, 6ksc – MtLigD A (mutant) + AMP

7k72 – MtLigD A + AMP + NAD

6kjm, 6krh – MtLigD A + AMP + nicotinamide ribose-MP

6kkv, 6lw8– MtLigD A + inhibitor

6ksd - MtLigD (mutant) + nicotinamide mononucleotide

6kdu - MtLigD (mutant) + AMP + nicotinamide mononucleotide

1v9p, 1dgs – LigD – Thermos filiformis

1b04 – LigD adenylation domain (mutant) – Geobacillus stearothermophilus

4glw – LigD A + NMN + inhibitor – Streptococcus pneumoniae

4glx – EcLigD + DNA + inhibitor - Escherichia coli

5tt5 - EciLigD + NAD

3pn1, 4uco, 4ucr, 4ucs, 4uct, 4ucu, 4ucv, 4ufz – HiLigD adenylation domain + inhibitor – Haemophilus influenza

3uq8 - HiLigD adenylation domain + NAD

LigD

2q2t – CvLigD + DNA + AMP + CMP – Chlorella virus

6imj, 6imk, 6iml, 6imn – LigD + DNA – African swine fever virus

6gdr – LigD + DNA – Alteromonas mediterranea

6dt1 – T4LigD + DNA – phage T4

5wfy – T4LigD DNA-binding domain

2q2u, 1p8l, 1fvi - CvLigD + DNA + mononucleotide

2owo – LigD + DNA + AMP + CMP – Escherichia coli

3qwu – LigD – Aquifex aeolicus

1l7b – LigD BRCT domain – Thermos thermophilus - NMR

3rr5 – LigD - Thermococcus

6wbo - LigD + AMP – Thermococcus gammatolerans

5frq - LigD + DNA polymerase III subunit β – Helicobacter pylori

Mammalian LigD I

1x9n – hLigD I + DNA + AMP + CMP – human

8b8t - hLigD I + PCNA – Cryo EM

7qnz - hLigD I + PCNA + DNA – Cryo EM

7qo1 - hLigD I + PCNA + FEN1 + DNA – Cryo EM

6p09, 6p0a, 6p0b, 6p0c, 6p0d, 7kr3, 7kr4, 7sx5, 7sxe, 7sum - hLigD I + DNA + AMP

6p0e, 6q1v, 7l34, 7l35 - hLigD I (mutant) + DNA + AMP

2od8 – LigD I residues 32-53 + PCNA

Mammalian LigD III

3l2p – hLigD III residues 257-833 + DNA

1uw0 - hLigD III zinc-finger domain residues 1-117 – NMR

1imo, 1in1 - hLigD III BRCT domain – NMR

3pc7 - hLigD III BRCT domain 932-1009

3qvg - hLigD III BRCT domain + XRCC1

3pc8 - hLigD III BRCT domain (mutant) + XRCC1

Mammalian LigD IV; Domains - catalytic 1-609; DNA-binding 1-240; adenylation 268-405; BRCT 654-911

3w5o - hLigD IV catalytic domain

3ii6, 1ik9 – hLigD IV C-terminal BRCT domains + DNA repair protein XRCC4

2e2w - hLigD IV BRCT domain 654-759 - NMR

3vnn - hLigD IV adenylation domain

4hto, 7d9k - hLigD IV DNA-binding domain

7d9y - hLigD IV DNA-binding domain (mutant)

4htp - hLigD IV DNA-binding domain + artemis protein peptide

3w1b, 3w1g - hLigD IV adenylation and DNA-binding domains + artemis protein peptide

6bkg, 6bkf - hLigD IV catalytic domain + DNA + AMP

7lsy, 7lt3, 7nfc, 7nfe - hLigD IV in NHEJ short-range synaptic complex – Cryo EM

1z56 – LigD IV + ligase interacting factor 1 - yeast

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

Retrieved from "http://proteopedia.org/wiki/index.php/DNA_ligase_3D_structures"

Category: Topic Page

DNA ligase 3D structures

From Proteopedia

3D Structures of DNA ligase

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox