Farnesyl diphosphate synthase 3D structures

1zw5, 2f7m, 4xqr, 4xqs, 4xqt – hFPS – human

1fps– cFPS – chicken

1ubv – cFPS (mutant)

5hxn – z,z-FPS – tomato

5hxo – z,z-FPS (mutant)

1rtr– FPS – Staphylococcus aureus

1yhk, 5qqc, 6r04, 3iba, 3icz, 3icm, 3icn, 1yhl, 6se2, 6sfa – TcFPPS – Trypanosoma cruzi

6vjc, 6w71, 4k10, 4jzb, 4jzx– LmFPPS – Leishmania major

3lvs, 3m0g – FPS – Rhodobacter capsulatus

3m9u – LbFPS – Lactobacillus brevis

5ayp – FPS – Geobacillus stearothermophilus

6ww1 – LmFPS (mutant) – Leishmania major

4ryp – TbFPS –Trypanosoma brucei

3ts7 – FPS – Methylococcus capsulatus

1yq7, 1yv5, 2f89, 2f8c, 2f92, 2f94, 2f9k, 2rah, 2opn, 2vf6, 3b7l, 2opm, 3n1v, 3n1w, 3n3l, 3n45, 3n46, 3n49, 3n5j, 3n6k, 3n5h, 4dem, 4ga3, 4jvj, 4pvx, 4pvy, 4rxa, 5dgn, 5diq, 5djp, 5djr, 5djv, 5juz, 5jv0, 5jv1, 5jv2, 5ksx, 5ygi, 6n7y, 6n7z, 6n82, 6n83, 6oag, 6oah - hFPS + inhibitor

2qis, 3cp6, 3rye, 3s4j, 4n9u - hFPS (mutant) + inhibitor

4kfa, 4kpj, 4kq5 - hFPS (mutant) + osteoporosis drug

4lpg, 4lph, 4n1z, 4p0x - hFPS + drug

4nfi, 4nfj, 4nfk, 4qxs, 4qpf, 5cg5 - hFPS + bisphosphonate

4ng6, 4nke, 4nkf, 4nua, 4ogu, 4q23 - hFPS (mutant) + bisphosphonate

5dgm, 5dgs - hFPS + monophosphonate

5ja0 - hFPS + FPP

1ubw, 1ubx - cFPS (mutant) + GDP

1uby - cFPS (mutant) + dimethylallyl PP

6b07, 6b02, 6b04, 6b06 – FPS + inhibitor – spruce budworm moth

5hxp – z,z-FPS (mutant) + IPP

5hxq – z,z-FPS (mutant) + DMSPP

2i19, 2ewg, 2ogd, 2p1c, 3dyg, 3dyh, 3efq, 3egt, 4rxe, 5ael, 5afx - TbFPS + inhibitor

4rxd – TbFBS + risedronate

2for– FPS + IPP – Shigella flexneri

4jzb, 4jzx, 4k10 – Leshmaniasis major FPS + inhibitor

3id0, 3iba, 3ick, 3icm, 3icn, 3icz, 4rxc, 5ahu, 5qpd, 6sdn, 6sdo, 6sdp, 6sdq, 6sf8, 6sf9, 6shv, 6si5 – TcFPS + inhibitor

6t7n – TcFPS + IPP

5qpe, 5qpk, 5qpo, 5qq3, 5qq8 – TcFPS + imidazole inhibitor

5qpg, 5qpn, 6r08 – TcFPS + indole inhibitor

5qpf, 5qq1, 6r09, 6r0a, 6r0b – TcFPS + piperazine inhibitor

6r06 – TcFPS + piperidine inhibitor

5qph, 5qq0 – TcFPS + morpholine inhibitor

5qpi, 5qpw, 5qpy, 5qq5, 5qqa – TcFPS + pyrazole inhibitor

5qps – TcFPS + oxazole inhibitor

5qpj, 5qpu, 5qq9 – TcFPS + acetamide inhibitor

5qpq – TcFPS + ethanamide inhibitor

5qpv – TcFPS + caboxamide inhibitor

5qpl, 5qpm, 5qpp, 5qpr, 5qpz, 5qq4 – TcFPS + urea inhibitor

5qpt – TcFPS + thiazine inhibitor

5qq2, 6r07 – TcFPS + thiophene inhibitor

5qpx – TcFPS + quinoline inhibitor

5qq6, 5qq7 – TcFPS + pyrrolidine inhibitor

6r05 – TcFPS + pyridine inhibitor

5qqb – TcFPS + benzodiazo inhibitor

3pde – LbFPS + IPP

6vjc – LmFPS (mutant) + inhibitor

4llt - RdFPS + IPP – Roseobacter denitrificans

7my6 - FPS + IPP – Synechococcus elongatus<br />

2f8z, 4h5e - hFPS + IPP + inhibitor

4kpd, 4kqs, 4kqu - hFPS (mutant) + IPP + osteoporosis drug

4p0v, 4p0w - hFPS + 2 drugs

4h5c, 4h3c, 4h5d, 4lfv - hFPS + phosphate + inhibitor

5cg6 - hFPS + IPP + bisphosphonate

4l2x - hFPS + PP + inhibitor

5hxt – z,z-FPS (mutant) + DMSPP + IPP

1rqi – EcFPS + IPP + dimethylallyl S-thioloPP – Escherichia coli

1rqj - EcFPS + IPP + inhibitor

1yhl – TcFPS + dimethylallyl PP + inhibitor

1yhm, 3iba, 3ick, 3icm, 3icn, 3icz, 4dwb, 4dwg, 4dxj, 4dzw, 4e1e - TcFPS + IPP + inhibitor

3ez3 - PvFPS + IPP + inhibitor – Plasmodium vivax

3dyf - TbFPS + IPP + inhibitor

4lls - RdFPS + IPP + geranyl derivative