Galactosidase 3D structures

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3D Structures of Galactosidase

Updated on 11-March-2023

α-Galactosidase

3hg2, 3gxn, 1r46, 1r47, 3s5y, 3s5z – hAgal A - human

3lx9, 3lxa, 3lxb, 3lxc, 3tv8 - hAgal A (mutant)

3h53 - hAgal B (mutant)

1uas – Agal – rice

3lrk – yAgal 1 (mutant) – yeast

3lrl, 3lrm – yAgal 1 (mutant) + polysaccharide

1zy9, 5m0x – TmAgal – Thermotoga maritima

3a24 – BtAgal – Bacterioides thetaiotamicron

3a5v – Agal I – Mortierella vinacea

3mi6 – Agal – Lactobacillus brevis

1szn – HjAgal – Hypocrea jecorina

2xn0, 2xn1 – LaAgal – Lactobacillus acidophilus

4fnp – GsAgal (mutant) – Geobacillus stearothermophilus

4fnq, 4fnr, 4oif – GsAgal

4xpo - PsBgal – Pedobacter saltans

4xpr - PsAgal (mutant)

6f4c - Agal – Nicotiana benthamiana

6jhp - Agal – Paecilomyces

6lcj - TtAgal – Thermus thermophilus

6phu – SpAgal – Streptococcus pneumoniae<br />

6y2k - Agal – Marinomonas

α-galactosidase binary complex

3h54 - hAgal B (mutant) + polysaccharide

3h55 - hAgal B (mutant) + galactose

3igu - hAgal B (mutant) + intermediate

3hg3, 3hg5 - hAgal A (mutant) + galactose

3gxp - hAgal A + galactose

3hg4 – hAgal A + intermediate

3gxt – hAgal A + imino sugar

4nxs - hAgal + jirimycin derivative

6ibk, 6ibm, 6ibr, 6ibt - hAgal A + trisaccharide + cyclosulfamidate

7exq, 7exr - Agal + saccharide – Arabidopsis thaliana

1t0o – HjAgal + galactose

2xn2 - LaAgal + galactose

4xpp - PsAgal + galactose

4xpq - PsAgal + fucose

4xps - PsAgal (mutant) + galactopyranoside derivative

4fns - GsAgal (mutant) + jirimycin derivative

4fnt, 4fnu – GsAgal + galactoside

5e1q - BtAgal + Gal-Lac

5m12, 5m16, 5m1i, 6gx8, 6gwg, 6gvd - TmAgal + sugar

6gwf, 6gta - TmAgal (mutant) + sugar

6lck, 6lcl - TtAgal + saccharide

6phv - SpAgal + galactopyranoside derivative

6phw, 6phx, 6phy, 6pi0 - SpAgal (mutant) + oligosaccharide

β-Galactosidase

3w5f – toBgal – tomato

5iaz - rBgal C-terminal - NMR

3og2 – TrBgal – Trichoderma reesei

1hn1, 1dp0, 1f4a, 1f4h, 4v41, 4v40, 4ttg, 6drv - EcBgal - Escherichia coli

3muy, 3i3e, 3iap, 3iaq, 3dym, 3dyp, 1px3, 3sep, 3t0a, 3t2o, 3vd3, 3vd5, 3vda, 4duv – EcBgal (mutant)

3j7h, 6cvm, 6drv, 6x1q – EcBgal – cryo EM

3dec, 3d3a, 3bga, 5mt2, 5mui, 5muj, 6euf, 6euj – BtBgal

6etz, 6h1p, 6zjv - ArBgal – Arthrobacter

1yq2, 6se8, 6zjp - ArBgal (mutant)

1uwi, 4eam, 5i3d - SsBgal (mutant) - Sulfolobus solfataricus

1uwq, 1gow – SsBgal

1kwg – TtBgal – Thermus thermophilus

1tg7 – PeBgal – Penicillium

3tts, 4mad, 7cwi – BcBgal – Bacillus circulans

4ypj - BcBgal (mutant)

4ha3, 4ha4 – Bgal – Acidilobus saccharovorans

3wq8, 6jow – Bgal – Pyrococcus furiosus

4cu6, 4cu8 – SpBgal catalytic module residues 137-985– Streptococcus pneumoniae

4cu9 – SpBgal carbohydrate-binding module II residues 1822-1998

4cua – SpBgal carbohydrate-binding module I residues 1463-1645

5xb7 - BaBgal – Bifidobacterium animalis

4uoq - BaBgal (mutant)

5vym - Bgal – Bifidobacterium adolescentis

5nav, 5naq - Bgal – Lactobacillus plantarum

5yhs - BacBgal – Bacillus

3ob8, 3oba – Bgal – Kluyveromyces lactis

5dfa - GsBgal (mutant)

5dmy, 6quc, 7nit - BbBgal – Bifidobacterium bifidum

5e9a - Bgal - Rahnella

5euv - ParBgal - Paracoccus

5ifp - AnBgal – Aspergillus niger

6mvh - Bgal – Roseburia hominis

6hpd - Bgal – Formosa agariphila

6s6z, 6sd0 - TmBgal – Cryo EM

6lvw - Bgal – Halorubrum lacusprofundi

6u7i - FpBgal – Faecaibavterium prausnitzii

6u7j - Bgal – Clostridium

6m4e - Bgal – Hamamotoa singularis

6ld6 - BdBgal – Bifidobacterium dentium

6ec6, 6jz1 - RgBgal – Ruminococcus gnavus

7kmn - XcBgal – Xanthomonas citri

4d1i - CjBgal – Cellvibrio japonicus

7f1n - Bgal - Thermofilum

7sf2 - Bgal – Bacterioides cellulosilyticus

β-Galactosidase binary complex with galactose

3thc - hBgal + galactose

3wf3 - hBgal + galactose + NAG

3w5g, 6ik5 - toBgal + galactose

6ik6, 6ik7, 6ik8 - toBgal (mutant) + galactobiose

1kwk – TtBgal + galactose

3ogr – TrBgal + galactose

3e1f, 1jz7 - EcBgal (mutant) + galactose

3t09, 3t0d, 3t2q, 3vd7, 3vdb - EcBgal (mutant) + galactose derivative

4iug - Bgal + galactose – Aspergillus oryzae

3tty - BcBgal + galactose

4cub, 4e8c, 4e8d – SpBgal carbohydrate-binding module I + galactose

4cuc – SpBgal catalytic module (mutant) + galactose

4uni - BaBgal + galactose

4uoz - BaBgal (mutant) + galactose

4ucf, 4uzs, 6qub, 6qud - BbBgal + galactose

5ldr - ParBgal + galactose

6eon - BtBgal + galactose

1xc6 - PeBgal + galactose

6sed - ArBgal + galactose

6zjq, 6zjs, 6zjw - ArBgal (mutant) + galactose

6zju - ArBgal (mutant) + saccharose

5yif - BacBgal (mutant) + galactose

7kmo - XcBgal + galactose

6eui - BtBgal + galactose

β-Galactosidase other complexes

3thd – hBgal + jirimycin derivative

3wez - hBgal + NOEV

3wf0, 3wf1 - hBgal + pyrimidine derivative

3wf4 - hBgal (mutant) + pyridine derivative

3wf2 - hBgal + piperidine derivative

7kdv - Bgal + cathepsin A – mouse – Cryo EM

7bzm - rBgal + glucoimidazole

3ogs - TrBgal + IPTG

3ogv – TrBgal + inhibitor

2ceq, 1uwr, 1uws, 1uwt, 1uwu, 2cer - SsBgal + inhibitor

4ean, 5ixe – SsBgal + indole derivative

3muz, 3i3d, 3dyo, 1px4, 1jyx, 3t08, 3t0b, 3t2p, 3vd4, 3vd9, 3vdc- EcBgal (mutant) + IPTG

3mv0, 3i3b, 3czj, 4v45, 1jz2, 1jz3, 1jz4, 1jz5, 1jz6 - EcBgal (mutant) + intermediate

3mv1 - EcBgal (mutant) + guanidinium

1jyn, 4v44, 1jz8 - EcBgal (mutant) + lactose derivative

1jyn, 1jyw, 1jyv - EcBgal (mutant) + substrate

5a1a - EcBgal + inhibitor – Cryo-EM

1jz6 - EcBgal (mutant) + inhibitor

4duw - EcBgal (mutant) + allolactose

6tsk - EcBgal + ribose – Cryo EM

4dux - EcBgal (mutant) + ribose

6tte - EcBgal + galactopyranoside derivative – Cryo EM

6tsh - EcBgal + jirimycin derivative – Cryo EM

6kuz, 7brs, 7btk - EcBgal (mutant) + probe

6leg, 6lej, 6lel, 6lem - EcBgal + Gauche drug

4ckd – EcBgal + antibody

4cu7 - SpBgal catalytic module + Gaucher drug

6nzg - BuBgal + aziridine derivative – Bacterioides uniformis

6seb, 6sec - ArBgal + galactopyranoside derivative

6se9, 6sea - ArBgal (mutant) + lactose

6zjx - ArBgal (mutant) + saccharose

6zjr, 6zjt - ArBgal (mutant) + lactulose

7cwd - BcBgal + disaccharide

6ld0, 6ldb, 6ldc, 6ldd - BdBgal + Gauche drug

6jz2, 6jz6, 6jz7 - RgBgal + Gauche drug

6jz4, 6jz8 - RgBgal + glucaro lactone

5mgc, 5mgd - RgBgal (mutant) + disaccharise

6jz3 - RgBgal + drug

6mvf - FpBgal + FMN

6d4o - Bgal + glucuronic acid derivative – Lachnospira eligens

6euh - BtBgal + drug

6eug - BtBgal + galactoimidazole

7zvo - BtBgal + Ser + Ala

5jaw, 6tbf, 6tbg, 6tbh, 6tbi, 6tbj, 6tbk - CjBgal + inhibitor

4d1j - CjBgal + drug

5ift, 5ihr, 5juv - AnBgal (mutant) + saccharide

Endo-1,4-β-galactosidase

2xom, 2xon – TmEbgal carbohydrate-binding domain + β-galactotriose

1ups – Ebgal - Clostridium perfringens

2ygl, 2ygm – SpEbgal blood group A & B cleaving

4bf7 – Ebgal – Emericella nidulans

7pmo – Rggal

7q1w, 7q20 – Rggal (mutant) + polysaccharide

3,6-anhydro-α-L-galactosidase

3p2n, 5opq – AAgal – Zobellia galactanivorans

4ak5, 7ljj – BpAAgal – Bacterioides plebeius

4ak6 – BpAAgal (mutant)

4ak7, 7lnp – BpAAgal (mutant) + polysaccharide

7lk7 – BpAAgal + galactose

6-phospho-β-D-galactosidase

2pbg, 3pbg, 4pbg, 1pbg – Pgal (mutant) – Lactococcus lacti

2v4v – gal GH59 – Clostridium cellulolyticum

4zep – GsPgal + phospho-glucose

7m1r – Pgal – Bacillus licheiformis

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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Galactosidase 3D structures

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3D Structures of Galactosidase

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