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Glucagon-like peptide 2

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Glucagon-like peptide 2 (GLP-2) is a peptide hormone that binds to the Glucagon-like peptide 2 receptor (GLP-1). It has a role in digestion that is distinct from other peptide hormones derived from proglucagon (glucagon, GLP-1, glicentin-related pancreatic peptide)[1].

Structure

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References

  1. ↑ Mukherjee K, Xiao C. GLP-2 regulation of intestinal lipid handling. Front Physiol. 2024 Feb 14;15:1358625. PMID:38426205 doi:10.3389/fphys.2024.1358625
  2. ↑ Sun W, Chen LN, Zhou Q, Zhao LH, Yang D, Zhang H, Cong Z, Shen DD, Zhao F, Zhou F, Cai X, Chen Y, Zhou Y, Gadgaard S, van der Velden WJC, Zhao S, Jiang Y, Rosenkilde MM, Xu HE, Zhang Y, Wang MW. A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor. Cell Res. 2020 Dec;30(12):1098-1108. PMID:33239759 doi:10.1038/s41422-020-00442-0

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Karsten Theis

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