Glucocorticoid receptor 3D structures
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3D structures of glucocorticoid receptor
Updated on 14-March-2023
Glucocorticoid receptor
7kw7
- hGCR + Hsp90 + Hsp70 + HOP – human – Cryo EM
Glucocorticoid receptor residues 89-158
5va7
,
5va0
- hGCR + DNA
Glucocorticoid receptor DBD domain residues 391-480
6cfn
- hGCR DBD
4hn5
,
4hn6
,
5emp
,
5emq
,
5emc
,
5e69
,
5e6a
,
5e6b
,
5e6c
,
5e6d
,
5cbx
,
5cby
,
5cbz
,
6bqu
,
6x6d
,
6x6e
- hGCR DBD + DNA
5cc1
- hGCR DBD (mutant) + DNA
1gdc
,
2gda
,
1rgd
– rGCR DBD – NMR – rat
3g9p
,
3fyl
,
3g6p
,
3g6q
,
3g6r
,
3g6t
,
3g6u
,
3g8u
,
3g8x
,
3g97
,
3g99
,
3g9i
,
3g9m
,
3g9j
,
3g9o
,
1glu
,
1lat
,
1r4o
,
1r4r
- rGCR DBD + DNA
6bse
,
6bsf
- GCR DBD + DNA – cotton-top tamarin
Glucocorticoid receptor LBD domain residues 500-777 complex with NCOA peptide
4mdd
- hGCR LBD (mutant) + NCOA1 peptide + non-steroidal agonist
3h52
- hGCR LBD (mutant) + NCOA1 peptide + steroid
4udc
,
4udd
- hGCR LBD (mutant) + NCOA2 peptide
1m2z
,
3cld
,
3bqd
,
4lsj
,
4p6w
,
4p6x
,
1p93
- hGCR LBD (mutant) + NCOA2 peptide + steroid
3e7c
,
4csj
,
5g3j
,
5g5w
,
5g3j
- hGCR LBD (mutant) + NCOA2 peptide + non-steroidal agonist
3k23
- hGCR LBD (mutant) + NCOA2 peptide + prolinamide
6el9
,
6el6
,
6el7
,
5nft
- hGCR LBD + NCOA2 peptide + modulator
5nfp
,
6w9m
- hGCR LBD + NCOA2 peptide + drug
3gn8
- hGCR LBD + NCOA2 peptide + steroid
4e2j
- anGCR LBD + NCOA2 peptide + steroid - ancestral
3mne
,
3mno
,
3mnp
- GCR LBD (mutant) + NCOA2 peptide + steroid – mouse
Glucocorticoid receptor LBD domain other complexes
3ry9
- anGCR LBD ancestral + steroid
1nhz
– hGCR LBD (mutant) + steroid
5uc3
- hGCR LBD (mutant) + RU-486
3k22
- hGCR LBD (mutant) + transcriptional intermediary factor 2 peptide + alaninamide
7krj
- hGCR LBD (mutant) + Hsp90 + P23 – Cryo EM
6dxk
– hGCR LBD + antagonist
7prx
– hGCR LBD + PGC1A coactivator + modulator
7prw
– hGCR LBD + PGC1A coactivator + modulator + DNA
7prv
– hGCR LBD + PGC1A coactivator + DNA + drug
Glucocorticoid receptor 2
5ufs
– anGCR2 LBD + SHP coregulatory + triamcinolone acetonide
4e2j
– anGCR2 LBD ancestral + NCOA2 peptide + steroid
6nwl
– anGCR2 LBD ancestral + cortisol + PPARGC peptide
6nwk
,
6w9k
,
6w9l
– anGCR2 LBD ancestral + drug + PPARGC peptide
5uc1
– GCR2 LBD + RU-486 –
Heterocephalus glaber
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Michal Harel
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