Image:Summery for the mechanism.jpg
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Summary
The agonists and antagonists are anchored in the interdomain crevice of GBR1 by an overlapping set of residues. An antagonist confines GBR1 to the open conformation of the inactive state, while an agonist induces its domain closure for activation
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| Date/Time | User | Dimensions | File size | Comment | |
|---|---|---|---|---|---|
| (current) | 10:33, 25 July 2015 | Rana Saad (Talk | contribs) | 960×720 | 54 KB | The agonists and antagonists are anchored in the interdomain crevice of GBR1 by an overlapping set of residues. An antagonist confines GBR1 to the open conformation of the inactive state, while an agonist induces its domain closure for activation |
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