Janus kinase 3D structures

4e4l, 4e4n, 4e5w, 4ehz, 4ei4, 4fk6, 4i5c, 4k6z, 3eyg, 3eyh, 5e1e, 5hx8, 5khx, 6n77, 6n78, 6n79, 6n7a, 6n7b, 6n7c, 6n7d, 6elr, 6dbn, 4k77, 6bbu, 5wo4, 6w8l, 6hzu, 6rsb, 6rsc, 6rsd, 6rse, 6rsh, 6sm8, 6smb, 6tpe, 6tpf, 6vnb, 6vnc, 6vne, 6vnf, 6vng, 6vnh, 6vni, 6vnj, 6vnk, 6vnl, 6vnm, 6vs3, 6vsn, 6wtq - hJAK1 kinase domain + PTyr + inhibitor - human

5khw – hJAK1 kinase domain + PTyr + ADP

6c7y]] – hJAK1 kinase domain + PTyr + SOCY1 + ADP

6aah, 6aaj, 6vgl, 6vn8, 6wtn, 6wto – hJAK1 kinase domain + PTyr + drug

4l00 – hJAK1 pseudokinase domain

4l01 – hJAK1 pseudokinase domain (mutant)

5ixd, 5l04 – hJAK1 + IFN l receptor

5ixi – hJAK1 + IFN l receptor/IL10

6e2p – hJAK1 + leptin receptor

6e2q – hJAK1 + erythropoietin receptor

4fvp - hJAK2 kinase domain

3ugc, 4bbe, 4bbf, 3zmm, 2xa4, 4c61, 4c62, 5l3a, 5tq3, 5tq4, 5tq5, 5tq6, 5tq7, 5tq8, 6tpd – hJAK2 kinase domain (mutant) + inhibitor

3e62, 3e63, 3e64, 2w1i, 4ytc, 4ytf, 4yth, 4yti, 4zim, 5aep, 5cf4, 5cf5, 5cf6, 3io7, 3iok, 3kck, 3jy9, 3lpb, 3krr, 3q32, 3tjc, 3tjd, 3rvg, 4aqc, 4e4m, 4f09, 4hge, 4d0w, 4d0x, 4d1s, 4p7e, 4aep, 5cf8, 6ggh, 7ree – hJAK2 kinase domain + PTyr + inhibitor

2b7a, 3fup, 4e6d, 4e6q, 4f08 – hJAK2 kinase domain (mutant) + PTyr + inhibitor

6aaj – hJAK2 kinase domain (mutant) + PTyr + drug

4gl9 – mJAK2 kinase domain + PTyr + inhibitor + suppressor of cytokine signaling 3 + interleukin 6 receptor subunit β - mouse

4gfm, 4gmy, 4iva, 4ivb, 4ivc, 4ivd, 4ji9, 4jia, 5usy, 5usz, 5ut0, 5ut1, 5ut2, 5ut3, 5ut4, 5ut5, 5ut6, 6drw, 5wev - hJAK2 JH1 domain + PTyr + inhibitor

5hez - hJAK2 JH1 domain (mutant) + PTyr + inhibitor

6bbv, 6wtp, 7ll4, 7ll5, 7q7i, 7q7k, 7q7l, 7q7w, 7rn6, 7uyw - hJAK2 JH1 domain + inhibitor

7f7w – hJAK2 JH2 domain

6obb, 7t0p - hJAK2 JH2 domain + inhibitor

6brw, 6d2i, 6bs0, 6bss, 5wij, 5wik, 5wil, 5wim, 5win, 6g3c, 6m9h, 6oav, 6obf, 6obl, 6occ, 6x8e, 6xjk, 7jyo, 7jyq, 7t1t, 8b8n, 8b8u, 8b99, 8b9e, 8b9h, 8ba2, 8bab, 8bak, 8ex0, 8ex1, 8ex2 - hJAK2 JH2 domain (mutant) + inhibitor

8ba3, 8ba4 - hJAK2 JH2 domain (mutant) + drug

3ugc – hJAK2 JH2 domain (mutant)

4fvq, 4fvr, 5i4n – hJAK2 JH2 domain (mutant) + ATP

4z32 – hJAK2

1yvj – hJAK3 kinase domain (mutant) + PTyr + staurosporine analog

3lxk, 3lxl, 5wfj – hJAK3 kinase domain (mutant) + PTyr + inhibitor

3pjc, 4v0g, 4z16, 5lwm, 5lwn, 5toz, 6glb, 6gl9, 6gla, 6ny4, 6dud, 6da4, 7apf, 7apg, 7q6h, 7uyv – hJAK3 kinase domain + inhibitor

4hvd, 4hvg, 4hvh, 4hvi, 3zc6, 3zep, 4i6q, 4qps, 4rio, 4qt1, 5tts, 5ttu, 5ttv, 5vo6, 6db3, 6db4 – hJAK3 kinase domain (mutant) + inhibitor

5w86, 6hzv – hJAK3 kinase domain + PTyr + inhibitor

7c3n – hJAK3 kinase domain + PTyr + drug

6aak – hJAK3 kinase domain (mutant) + PTyr + drug

7t6f, 8ewy – mJAK + interferon lambda receptor 1