Lysine-specific histone demethylase 3D structures

2com, 2l3d - hLSD1 SWIRM domain 174-273 – human – NMR

5it3, 6e1f - hLSD1 SWIRM domain

2h94, 2dw4, 2z3y, 2z5u, 4fwe, 4fwj, 4gu1, 6nqm – hLSD1 170-833

2hko – hLSD1 (mutant)

2ejr, 3abt, 3abu – hLSD1 + tranylcypromine derivative

4gut, 4guu – hLSD1 + oxidoreductase

6nqu, 6kgo, 6kgp, 6kgq, 6kgr, 7vqs, 7vqt, 7vqu, 7w3l – hLSD1 + inhibitor

6nr5 – hLSD1 + phenelzine sulfate

7xw8 – hLSD1 + pteridine derivative

4fwf – hLSD1 + histone 3.1 peptide

4czz - hLSD1 + CoREST

5l3b, 5l3c, 5l3d - hLSD1 (mutant) + CoREST

7zry – hLSD1 + CoREST SANT1 and SANT2 domains 305-482

2iw5, 2uxn, 2uxx - hLSD1 SWIRM + amine oxidase domains + CoREST SANT1 and SANT2 domains

2v1d, 5x60, 5h6r, 5h6q - hLSD1 residues 123-852 + CoREST SANT1 and SANT2 domains + histone H3 residues 2-22 (mutant)

2x0l - hLSD1 residues 123-852 + CoREST SANT1 and SANT2 domains + histone H3 residues 1-16

2xaf, 2xag, 2xah, 2xaj, 2xaq, 2xas - hLSD1 residues 123-852 + CoREST SANT1 and SANT2 domains + tranylcypromine derivative

2y48 - hLSD1 residues 123-852 + CoREST SANT1 and SANT2 domains + zinc finger protein SNAIL N terminal

3zms, 3zmt, 3zmu, 3zmv, 3zmz, 3zn0, 3zn1 - hLSD1 residues 123-852 + CoREST SANT1 and SANT2 domains + zinc finger protein IA-1 peptide

4bay - hLSD1 residues 192-876 + CoREST residues 308-440

4kum - hLSD1 SWIRM + FAD domains + CoREST residues 289-485

6kgk - hLSD1 172-833 + CoREST

4uv8, 4uv9, 4uva, 4uvb, 4uvc - hLSD1 + CoREST + irreversible inhibitor

5l3e, 5lbq, 5lgn, 5lgt, 5lgu, 5lhg, 5lhh, 5lhi - hLSD1 + CoREST + reversible inhibitor

5l3f, 5l3g - hLSD1 + CoREST + polmyxin peptide

4xbf - hLSD1 + CoREST + RNA

4uxn, 5yjb, 6k3e, 6kgl, 6kgm, 6kgn, 6te1, 6tuy, 6w4k, 7e0g - hLSD1 + CoREST + pyrrolydine inhibitor

6s35, 7cdc, 7cdd, 7cde, 7cdf, 7cdg - hLSD1 + CoREST + peptide inhibitor

6vyp - hLSD1 + CoREST + histones + DNA

4gu1 – hLSD2

4gur, 4gus, 4hsu – hLSD2 + NPAC + histone 3.3 peptide

4gut – hLSD2 + NPAC

4guu – hLSD2 + NPAC + tranylcypromine

4gu0 – hLSD2 + histone 3.3 peptide

7xe1, 7xe2, 7xe3 – hLSD2 + inhibitor

6r25, 6r1t, 6r1u – hLSD2 + NPAC + histones 3,4,2A,2B + DNA – Cryo EM

5e6h – hLSD5A jmj domain

5isl, 5ivb, 5ivc, 5ive, 5ivf, 5ivj, 5ivv, 5ivy, 5iw0, 5iwf, 5k4l, 5v9p, 5v9t, 6bgu, 6bgv, 6bgw, 6bgx, 6bgy, 6bgz, 6bh0, 6bh1, 6bh2, 6bh3, 6bh4, 6bh5,6dq4, 6dq5, 6dq6, 6dq7, 6dq8, 6dq9, 6dqa, 6dqb, 6dqc, 6dqd, 6dqe, 6dqf – hLSD5A jmj domain + inhibitor

2kgg, 7klo – hLSD5A PHD domain - NMR

7klo – hLSD5A PHD1 domain - NMR

7klr – hLSD5A PHD1 domain + H3 peptide

3gl6 – hLSD5A PHD domain + H3 peptide

5c11 – hLSD5A PHD domain + H3 peptide

2kgi – hLSD5A PHD domain + H3 peptide - NMR

2jxj – hLSD5A ARID domain - NMR

2ma5 – hLSD5B zinc finger domain 3 - NMR

2mny – hLSD5B zinc finger domain 1 - NMR

2mnz – hLSD5B zinc finger domain 1 + histone 3 peptide - NMR

2eqy – hLSD5B ARID domain - NMR

5a3p – hLSD5B JmjC domain

5lwb, 5lw9, 5fun, 5fz0, 5fzk, 5fzl, 5fz9, 5fza, 5fzb, 5fzc, 5fyt, 5fyu, 5fyy, 5fyz, 5fz3, 5fz4, 5fz6, 5fz7, 5fpl, 5fpu, 5a3n, 5a3t, 5a3w, 6ein, 6eiu, 6eiy, 6ej0, 6ej1, 6ek6, 5fzm, 5fzi, 5fzg, 5fzf, 5fze, 5fzd, 5fz8, 5fyb, 6rbi, 6h4z, 6h50, 6h51, 6h52 – hLSD5B JmjC domain + inhibitor

5fzh, 5fz1 – hLSD5B JmjC domain + ligand

5fup, 5fys – hLSD5B JmjC domain + oxoglutarate

5fyv – hLSD5B JmjC domain + oxaloacetate

5fy9 – hLSD5B JmjC domain + pyruvate

5fy5 – hLSD5B JmjC domain + fumarate

5fy4 – hLSD5B JmjC domain + succinate

5fv3, 5a1f – hLSD5B JmjC domain + oxalyl glycine

6h4z, 6h50, 6h51, 6h52 – hLSD5B JmjC domain + inhibitor

4bbq – hKDM2A residues 567-681

6c16, 6byh – hKDM2A residues 888-932 + SKP1 + polyubiquitin

4tn7, 4qxh, 4qxc, 4qxb, 4qx8, 4qx7, 4qwn – hKDM2A residues 36-364 + histone peptide

6g8f, 6fuk, 6ful, 6ete – hKDM6A + inhibitor

3avr, 3avs – hKDM6A 880-1401 + H3 peptide + oxalylglycine