Malate Dehydrogenase 3D structures

From Proteopedia

3D Structures of Malate Dehydrogenase

Updated on 25-June-2023
The holo-MDH contains NAD or its derivatives while the apo-MDH lacks it.

Holo-MDH

2dfd, 4wlv – hMDH2 +NAD – human

7bsj, 7bsk, 7bsl – hMd2 (mutant) +NAD

4mdh – pMDH+NAD - pig

1o6z, 2x0r – HmMDH (mutant)+NAD - Haloarcula marismortui

1hlp – HmMDH+NAD

1x0i – AfMDH+NADH – Archaeoglobus fulgidus

2x0j - AfMDH+etheno-NAD

1hlp – HmMDH+NAD

1x0i – AfMDH+NADH

2x0j - AfMDH+etheno-NAD

1ib6, 1ie3 – EcMDH (mutant)+NAD - Escherichia coli

3i0p – MDH+NAD – Entamoeba histolytica

3gvh – BmMDH+NAD – Brucella melitensis

1wze – TfMDH (mutant)+NAD – Thermus flavus

1wzi - TfMDH (mutant)+NDP

1bmd – TfMDH+NAD

1y7t – TtMDH+NADPH – Thermus thermophilus

2cvq - TtMDH+NADP

1v9n – MDH+NADPH – Pyrococcus horikoshii

1z2i – MDH+NAD – Agrobacterium tumefaciens

1uxg, 1uxh, 1uxi, 1uxj, 1uxk, 1ur5 – ChaMDH (mutant)+NAD – Chloroflexus aurantiacus

1guz, 1guy, 1gv0 – CvMDH+NAD – Chlorobium vibrioforme

1civ – MDH+NADP – Flaveria bidentis

1b8u, 1b8v – AaMDH+NAD - Aquaspirillum arcticum

4i1i – LmMd + NAD – Leishmania major

5ujk – MeMd + NAD - Methylobacterium extorquens

5nuf, 5nue – Md1 + NAD – Arabidopsis thaliana

4uup – Md + NADH - Trichiminad

5kvv – MtMd + NADH – Mycobacterium tuberculosis

6ihd – MsMd + NAD – Metallosphaera sedula

6itl – Md + NAD – Mannheimia succiniciproducens

6y91 – PfMd + NAD – Plasmodium falciparum

6zn7 – BbMd + NADP – Bdellovibrio bacteriovorus

7f8d, 7x1l – GsMd (mutant) + NADH – Geobacillus stearophilus

Md binary complex

7rm9 – hMd1 + malonate

4wle – hMd2 + citrate

4wlf – hMd2 + malate

5kka – EcMd + inhibitor

5z3w, 6ka0 – EcMd + Ag

2cmd - EcMd + citrate

3gvi - BmMDH+ADP

2hjr – MDH+adenosine diphosphoribose – Cryptosporidium parvum

1bdm - TfMDH (mutant)+beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide

6bal – HiMd + malate - Haemophilus influenzae

6qss – Md + Tb derivative – Ignicoccus islandicus

6zng, 6znt – BbMd + acetyl-CoA

6znu – BbMd (mutant) + acetyl-CoA

Md ternary complex

4wlo – hMd2 + NADH + oxaloacetate

4wlu – hMd2 + NADH + malate

5mdh – pMd+NAD+alpha-ketomalonic acid

5zi2 – yMd + NAD + ADP - yeast

5zi4 – yMd + NAD + oxalacetate

4plh, 4plt – ApMd + NAD + oxamate – Apicomplexa

4plv, 4plw – ApMd + NAD + lactate

4ply – ApMd + NAD + malate

4ros – MeMd + oxaloacetate + ADPR

1emd – EcMd+NAD+citrate

6ihe – MsMd + NAD + malate

6itk – Md + NAD + malate – Corynebacterium glutamicum

6r8g – PfMd + NAD + thiazol derivative

7by9 – GsMd + NADH + oxalacetate – Geobacillus stearophilus

7bya – GsMd + adenosine diphosphoribose + oxalacetate

apo-MDH

7rrl – hMd1

4wln – hMd2

1mld – pMDH

7mdh – MDH – Sorghum

5zi3 – yMd

2j5r, 2j5k, 2j5q, 1d3a, 4jco – HmMDH

2hlp, 7q3x – HmMDH (mutant)

3hhp, 2pwz, 6ka1, 7cgc, 7cgd – EcMDH

7xqn – EcMd (mutant) br />

3fi9 – MDH – Porphyromonas gingivalis

3d5t - MDH – Burkholderia pseudomallei

2d4a – MDH – Aeropyrum pernix

1iz9, 4kde, 4kdf - TtMDH

1sev, 1smk – MDH – Citrullus lanatus

1gv1 – CvMDH

1b8p – AaMDH

3nep – Md – Salinibacter ruber

3p7m – Md – Francisella tularensis

3tl2 – Md – Bacillus anthracis

4e0b – Md – Vibrio vulnificus

4h7p - LmMd

4cl3 – ChaMd

4bgu – Md – Haloferax volcanii

4bgv – Md – Picrophilus torridus

5ulv – MeMd

4tvo – Md – Mycobacterium tuberculosis

6aoo – HiMd

5nfr – PfMd

4uuo – Md – Trichomonas vaginalis

6um4 – Md – Naegleria fowleri

6pbl – Md – Legionella pneumophila

7by8 – GsMd

6zn4, 6zn9, 6znj – BbMd

6zne, 6znk, 6znr – BbMd (mutant)

7aob – Md – Thermaerobacter marianensis

7nrz – Md – Trypanosoma cruzi