Plexin 3D structures

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03-September-2023

Plexin A

5l56, 5l59, 5l5c – mPLX-A1 extracellular domain segment 1-10 - mouse

5l7n – mPLX-A1 extracellular domain segment 7-10

3ryt - mPLX-A1 intracellular domain + Ras-related C3 botulinum toxin substrate

7y4p - hPLX-A1 extracellular domain 1-4 27-708 - human

7y4q - hPLX-A1 extracellular domain 1-4 + semaphorin

3q3j - hPLX-A2 binding domain + Rho-related GTP-binding protein Rho6

3al8, 3oky – mPLX-A2 + semaphorin-6A

4gza - mPLX-A2 + semaphorin-3A + neuropilin-1

3al9 – mPLX-A2 SEMA+PSI domain

3okt - mPLX-A2 extracellular domain segment 1-4

5l5g – mPLX-A2 extracellular domain segment 1-8

5l74 – mPLX-A2 extracellular domain segment 4-5

3ig3 - mPLX-A3 intracellular domain

4e74 - hPLX-A4 Rho GTPase-binding domain

5l5k, 5l5l – mPLX-A4 extracellular domain

5l5k – mPLX-A4 extracellular domain segment 1-10

5l5l – mPLX-A4 extracellular domain segment 1-8

5l5m, 5l5n – mPLX-A4 extracellular domain segment 1-7

7m0r – mPLX-A4 + neuropilin + semaphorin - CryoEM

6fkm, 6fkn - PLX-A + semaphoring – Drosophila melanogaster

Plexin B; Domains – extracellular 19-535; cytoplasmic 1511-2135; effector 1743-1862

8b3k - hPLX-B1 extracellular domain

2r2o – hPLX-B1 effector domain

2rex - hPLX-B1 effector domain + Rho-related GTP-binding protein Rho6

2jph - hPLX-B1 effector domain – NMR

3ol2 - hPLX-B1 extracellular domain + semaphorin 4D

3sua, 3su8 – hPLX-B1 cytoplasmic domain + RAS-related C3 botulinum toxin substrate

3hm6 - hPLX-B1 cytoplasmic domain + peptide

7vf3, 7vg7 - hPLX-B1 extracellular domain + peptide

5b4w - hPLX-B1 extracellular domain + peptide inhibitor

4e71 - hPLX-B2 effector domain

5e6p - hPLX-B2 cytoplasmic domain + Rho guanine
nucleotide exchange factor 11

8bb7, 8bf4 - mPLX-B1 extracellular domain + nanobody

7kdc – mPLX-B2 receptor binding domain 1463-1565 + RhoD

Plexin C

3kuz - hPLX-C1 ubiquitin-like domain

3nvn, 3nvq – hPLX-C1 + semaphorin 7A

6vxk - hPLX-C1 + semaphorin-like protein – Cryo EM

4m8n - PLX-C1 intracellular domain + RAP1B – zebra fish

Plexin D

3h6n - hPLX-D1 ubiquitin-like domain

5v6r - mPLX-D1 intracellular domain

5v6t - mPLX-D1 intracellular domain + GIPC1

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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Plexin 3D structures

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