Pyruvate kinase 3D structures

3bjf, 3bjt, 1t5a, 1zjh - hPyK M2 muscle - human

3g2g, 6b6u, 4qg6, 4qg8, 4qg9, 4qgc, 4yj5, 4wj8 - hPyK M2 muscle (mutant)

3srf, 3srh – hPyK M1 muscle

6wp3, 6wp4, 6wp5, 6wp6 – hPyK M2 muscle (mutant)

1pkm, 1pyk – PyK muscle – cat

1f3w, 8f5t – rPyK muscle – rabbit

1f3x, 7r6y - rPyK muscle (mutant)

4b2d - hPyK M2 muscle + fructose bisphosphate

4rpp - hPyK M2 muscle (mutant) + fructose bisphosphate

4fxj - hPyK M2 muscle + phenylalanine

6gg3 - hPyK M2 muscle + alanine

6gg4 - hPyK M2 muscle + phenylalanine

6gg5 - hPyK M2 muscle + tryptophan

6gg6 - hPyK M2 muscle + serine

6nub - hPyK M2 muscle (mutant) + serine

6nu1 - hPyK M2 muscle + cysteine

6nu5 - hPyK M2 muscle (mutant) + cysteine

6ttf, 6tti, 6ttq - hPyK M2 muscle + inhibitor – Cryo EM

6tth - hPyK M2 muscle + threonine – Cryo EM

6v74, 6v75 - hPyK M2 muscle + asparagine

6v76 - hPyK M2 muscle + valine

8g2e - hPyK muscle + activator

8f5u - rPyK muscle + pyruvate

3me3 – hPyK M1/M2 muscle + aniline derivative + fructose bisphosphate

4g1n - hPyK M1/M2 muscle + pyridazine derivative + oxalate

3h6o - hPyK M1/M2 muscle + pyridazine derivative + fructose bisphosphate

3gqy, 3gr4, 3u2z - hPyK M1/M2 muscle + piperazine derivative + fructose bisphosphate

8hmq, 8hmr, 8hms, 8hmu - hPyK muscle (mutant) + Pi + fructose bisphosphate

5x0i - hPyK M2 muscle (mutant) + serine + fructose bisphosphate

7l21 - hPyK M2 muscle (mutant) + oxalate + fructose bisphosphate

6jfb - hPyK M2 muscle + serine + phosphate

5x1v, 5x1w - hPyK M2 muscle + activator + fructose bisphosphate

4jpg - hPyK M1/M2 muscle + pyrimidine derivative +fructosebisphosphate

3srd - hPyK M1/M2 muscle + oxalate + fructose bisphosphate

4fxf - hPyK M1/M2 muscle + oxalate + ATP + fructose bisphosphate

3n25 – rPyK M1/M2 muscle + proline + Mn + pyruvate

2g50 - rPyK M1/M2 muscle + alanine + Mn + pyruvate

8f6m - rPyK muscle + Ala + Mn + ADP

1pkn - rPyK muscle + Mn + pyruvate

1aqf – rPyK muscle + Mg + phospholactate

1a49, 1a5u - rPyK muscle + ATP + oxalate

7qdn - hPyK liver (mutant)

2vgb – hPyK liver
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6nn5, 6nn7, 6nn8, 2vgf, 2vgg, 2vgi – hPyK liver (mutant)

6nn4 - hPyK M2 liver (mutant) + fructose bisphosphate

6ech, 6eck - PyK liver + fructose bisphosphate - rat

5sc8, 5sc9, 5sca, 5scb, 5scc, 5scd, 5sce, 5scf, 5scg, 5sch, 5sci, 5scj, 5sck, 5scl, 5sdt, 7qzu - hPyK liver + anthracene derivative + fructose bisphosphate

7frv, 7frw, 7frx, 7fry, 7frz, 7fs0, 7fs1, 7fs2, 7fs3, 7fs4, 7fs5, 7fs6, 7fs8, 7fs9, 7fsa, 7fsb, 7fsc, 7fsd - hPyK liver + modulator + fructose bisphosphate

4ima, 4ip7 - hPyK liver (mutant) + citrate + adenosine + fructose bisphosphate

6du6 – PyK - mosquito

1pky, 4yng, 6k0k – EcPyK - Eschericia coli

1e0t, 1e0u, 8edq, 8edr, 8eds, 8edt, 8eq0, 8eq1, 8eq3, 8eu4 - EcPyK (mutant)

3t05, 3t0t – SaPyK – Staphylococcus aureus

3qtg – PyK – Pyrobaculum aerophilum

4krz - TcPyK – Trypanosoma cruzei

5wrp - MtPyK – Mycobacterium tuberculosis

3hqn, 3e0w, 1pkl – LmPyK – Leishmania mexicana

3khd, 7z4m – PfPyK – Plasmodium falciparum

7z4q, 7z4r - PfPyK (mutant)

3gg8, 3eoe – PyK – Toxoplasma gondii

3ma8, 4drs – CpPyK – Cryptosporidium parvum

2e28 - PyK (mutant) – Geobacillus stearothermophilus

7oo1 – PaPyK – Pseudomonas aeruginosa

7ueh – PyK – Zymomonas mobilis

8ias - SpPyK – Streptococcus pneumoniae

3qv9 – TcPyK + Ponceau S

3qv6 – LmPyK + acid blue 80

3e0v – LmPyK + sulfate

3hqq - LmPyK + fructose bisphosphate

3qv8 – LmPyK + benzothiazole

3pp7 – LmPyK + suramin

3is4, 3ktx – LmPyK + pyrenetetrasulfonic acid

3t07 – SaPyK + bis-indole alkaloid

4hyw – TbPyK + fructose bisphosphate – Trypanosoma brucei

6su1, 6su2 – PyK + citrate – Trypanosoma congolense

5ws8 - MtPyK + oxalate

6p0y - CpPyK + ADP

8iav - SpPyK + fructose bisphosphate

8iat - SpPyK + oxalate

8iaw - SpPyK + phosphoenolpyruvate

7z4n -PfPyK + pyruvate

1a3w – yPyK + Mn + phosphoglycolic acid + fructose bisphosphate – yeast

1a3x - yPyK + Mn + phosphoglycolic acid

4hyv – TbPyK + phosphoenolpyruvate + fructose bisphosphate

4kct – TbPyK + pyruvate + fructose bisphosphate

4kcu – TbPyK + malate + fructose bisphosphate

4kcv – TbPyK + oxoglutarate + fructose bisphosphate

4kcw – TbPyK + oxalate + fructose bisphosphate

4ks0 – TcPyK + oxalate + fructose bisphosphate

5ws9 – MtPyK + oxalate + AMP + ATP

5wsa – MtPyK + oxalate + glucose-6-phosphate

5wsb, 5wsc – MtPyK + oxalate + glucose-6-phosphate + AMP

6ito – MtPyK + oxalate + ribose-5-phosphate + AMP

3hqo – LmPyK + ATP + oxalate

3hqp - LmPyK + ATP + oxalate + fructose bisphosphate

3qv7 – LmPyK + acid blue 25 + Ponceau S

3srk – LmPyK + saccharine + inhibitor

6qxl – PaPyK + malonate + glucose-6-phosphate + Mg

6ksh – PfPyK + oxalate + ATP

8iax - SpPyK + fructose bisphosphate + phosphoenolpyruvate

8iau - SpPyK + fructose bisphosphate + oxalate