From Proteopedia

3D structures of Serine hydroxymethyltransferase

Updated on 15-November-2023

SHMT

6dk3 – hSHMT 2 – human

5x3v – hSHMT 2 (mutant)

7pzz – AtSHMT 2 – Arabidopsis thaliana

7q00 – AtSHMT 4

7qpe – AtSHMT 6

7qx8 – AtSHMT 7

3gbx – SHMT – Salmonella typhimurium

3n0l – SHMT – Campylobacter jejuni

3pgy – SHMT + glycine – Staphylococcus aureus

4mso – BcSHMT – Burkholderia cenocepacia

3ecd – SHMT – Burkholderia pseudomallei

4bhd – MjSHMT – Methanocaldococcus jannaschii

4p3m – SHMT – Psychromonas ingrahamii

4wxb – StSHMT – Streptococcus thermophilus

6ti3 – StSHMT (mutant) + threonine

5vc2, 6f93 – SHMT – Helicobacter pylori

5vmb – SHMT – Acinetobacter baumannii

5z0y – SHMT – Pichia pastoris

7qcw – SHMT – Pseudomonas chlororaphis <br /

SHMT + PLP

1bj4 - hSHMT 1 + PLP

6fl5 – hSHMT 1 (mutant) + PLP

4pvf, 8aql, 8qi7, 8ssj – hSHMT 2 + PLP derivative

1cj0, 1rv4, 1rvu – rSHMT 1 (mutant) + PLP – rabbit

1eji – SHMT + PLP derivative – mouse

6uxh, 6uxi, 6uxk , 6uxl– sbSHMT 8 + PLP derivative – soybean

6cd0, 6cd1 – bmSHMT 3 + PLP derivatives - barrel medic

2dkj – TtSHMT + PLP – Thermus thermophilus

8suj – TtSHMT + PLP derivative

1kkj – GsSHMT + PLP – Geobacillus stearothermophilus

1yjz, 2vgs, 2vi8, 2vmn, 2vmp, 2vmr, 2vmv, 2w7d, 2w7f, 2w7i – GsSHMT (mutant) + PLP

3g8m – EcSHMT (mutant) + PLP – Eschericha coli

4j5u – SHMT + PLP derivative – Rickettsia rickettsia

4n0w - BcSHMT + PLP

4uqv - MjSHMT + PLP

4o6z – SHMT (mutant) + PLP – Plasmodium falciparum

3h7f – MtSHMT + PLP derivative – Mycobacteria tuberculosis

6ymd, 6yme, 6ymf – MtSHMT + PLP derivative – Aphanothece halophytica

6ti1, 6ti4 – StSHMT (mutant) + PLP derivative

7e13 - SHMT + PLP – Erigeron canadensis

4pff – PvSHMT + PLP – Plasmodium vivax

7ujh, 7uji, 8dom – GmSHMT (mutant) + PLP derivative – Glycine max

SHMT binary complex + PLP

8a11 - hSHMT + RNA + PLP derivative – Cryo EM

1rv3, 1rvy - rSHMT 1 (mutant) + glycine + PLP

1ls3 - rSHMT 1 + formyl hydrofolate derivative + PLP derivative

6uxj - sbSHMT 8 + formyl hydrofolate derivative + PLP

6ccz – bmSHMT 3 + selenourea + PLP derivative

1dfo – EcSHMT + formyl hydrofolate + PLP derivative

1kkp – GsSHMT + serine + PLP

1yjy, 2vgu, 2via, 2vmt, 2vmw, 2w7k – GsSHMT (mutant) + serine + PLP

2vmx, 2w7g, 2w7l – GsSHMT (mutant) + threonine + PLP

1kl1 – GsSHMT + glycine + PLP

1yjs, 2vgt, 2vgv, 2vgw, 2vi9, 2vib, 2vmo, 2vmq, 2vms, 2vmu, 2vmz, 2w7e, 2w7h, 2w7j, 2w7m – GsSHMT (mutant) + glycine + PLP

4ot8 - BcSHMT + serine + PLP

4otl - BcSHMT + glycine + PLP

4tn4, 5gvk, 5gvl, 5gvm, 5gvn, 5gvp, 5yfy, 5yg0, 5yg1, 5yfz, 5yg2, 5yg3, 5yg4, 5xms, 5xmt, 5xmu, 5xmv – PvSHMT + inhibitor + PLP derivative – Plasmodium vivax

5xmp, 5xmq, 5xmr – PvSHMT (mutant) + inhibitor + PLP derivative

4wxf – StSHMT + glycine + PLP derivative

6yrw – StSHMT (mutant) + Ser + PLP

4wxg – StSHMT + allo-threonine + glycine

SHMT ternary complex + PLP

6h3c – hSHMT 2 in Brisc and Brca1-A complex – Cryo EM

6r8f – hSHMT 2 (mutant) in Brisc and Brca1-A complex – Cryo EM

6qvg, 6qvl – hSHMT 2 + PLP + antifolate drug

8fjt, 8fju – hSHMT 2 + PLP + Gly + inhibitor

8fsd – sbSHMT + THF derivative + PLP + Gly

5v7i – hSHMT 2 + inhibitor + glycine + PLP

6smn – AtSHMT 2 + PLP + antifolate drug

6smw – AtSHMT 2 + PLP derivative + antifolate drug

6smr – AtSHMT 4 + PLP derivative + antifolate drug

1kl2 – GsSHMT + formyl hydrofolate + glycine + PLP

2vmy – GsSHMT (mutant) + formyl hydrofolate + glycine + PLP

1eqb - EcSHMT (mutant) + formyl hydrofolate + glycine + PLP

6tgh – StSHMT (mutant) + Ser + PLP derivative + pyridine derivative

6uld – MtSHMT + Ser + Gly + PLP

4tn4, 5gvk, 5gvl, 5gvm, 5gvn, 5gvp, 5xms, 5xmt, 5xmu, 5xmv, 5yfy, 5yg0, 5yg1, 5yg4 – PvSHMT + inhibitor + PLP derivative

5xmp, 5xmq, 5xmr – PvSHMT (mutant) + inhibitor + PLP derivative

7x5o – EfSHMT + THF derivative + PLP derivative – Enterococcus faecium

7v3d – EfSHMT + PLP + inhibitor

7x5n – EfSHMT + PLP derivative + inhibitor

8ssy – TtSHMT + PLP derivative + Ser

8dsk – GmSHMT + THF derivative + Gly + PLP derivative

SHMT other complexes

7byi – hSHMT 2 + carbenoxolone

6h3c – hSHMT 2 in BRISC complex – Cryo EM

4oyt – PvSHMT + Gly + folinic acid