TRNA methyltransferase 3D structures

From Proteopedia

3D structures of tRNA methyltransferase

Updated on 20-August-2024 - For a general description of the protein see TRNA methyltransferase

tRNA to N1 of guanine methyltransferase

6w14 – MsTrm – Mycobacterium smegmatis

6w15 – MsTrm + SAH

7kff – CdTrm – Corynebacterium diphtheriae

3knu, 8sh4 – ApTrm – Anaplasma phagocytophilum

tRNA guanine 9 N1 methyltransferase

4jwg – fyTrm – fission yeast

4jwf, 4jwh – fyTrm + SAH

4jwj – yTrm + SAH – yeast

tRNA guanine 37 N1 methyltransferase or TrmD

1oy5 – AaTrm – Aquifex aeolicus

3ief – Trm – Bartonella henselae

1uaj – HiTrm – Haemophilus influenzae

3ky7 – SaTrm – Staphylococcus aureus

3quv, 6nvr, 7rey – MaTrmD – Mycobacterium abscessus

5hjj, 5yac – PabTrm – Pyrococcus abyssi

6jki – PaTrmD – Pseudomonas aeruginosa

5zhi – MtTrm – Mycobacterium tuberculosis

7myq – AbTrm – Acinetobacter baumannii

Complexes of tRNA guanine 37 N1 methyltransferase

1uak, 4yvg – HiTrmD + SAM

1ual, 1uam – HiTrm + SAH

3axz – HiTrmD + adenosine

4mcb, 4mcc, 4mcd – HiTrmD + inhibitor

4yvh – HiTrmD + SFG

4yvi, 4yvj, 4yvk – HiTrmD + SFG + tRNA

5d9f, 4ypw, 4ypx, 4ypy, 4ypz, 4yq0, 4yq1, 4yq2, 4yq3, 4yq4, 4yq5, 4yq6, 4yq7, 4yq8, 4yq9, 4yqa, 4yqb, 4yqc, 4yqg, 4yqi, 4yqj, 4yqk, 4yql, 4yqn, 4yqo, 4yqp, 4yqq, 4yqr, 4yqs, 4yqt, 4yqd – HiTrmD + SAM competitive

2yx1 – MjTrm + SFG – Methanocalcococcus jannaschii

3ay0 – MjTrm5 + adenosine

4h3y, 4h3z – Trm + SAH – Burkholderia phymatum

4ig6 – ApTrm + SAH

1p9p – EcTrm + SAH – Escherichia coli

4gek, 4iwn – EcTrm + SAM derivative

5hr7 – EcTrm + tRNA-Glu

5hji, 5hjm – PabTrm + adenosine derivative

5hjk – PabTrm + SAH

6qo2, 6qo3, 6qo4, 6qo6, 6qoa, 6qoc, 6qod, 6qoe, 6qof, 6qog, 6qoh, 6qoi, 6qoj, 6qok, 6qol, 6qom, 6qon, 6qoo, 6qop, 6qoq, 6qor, 6qos, 6qot, 6qou, 6qov, 6qow, 6qox, 6qqq, 6qqr, 6qqt, 6qqu, 6qqv, 6qqw, 6qqz, 6qr0, 6qr1, 6qr2, 6qr3, 6qr4, 6qr7, 6qr9, 6qra, 6qrc, 6qrd, 6qre, 6qrf, 6qrg – MaTrmD + inhibitor

6nw6 – MaTrmD + SAM

6nw7, 7rez, 7rf0 – MaTrmD + SAH

6joe, 6jof, 5zhm, 5zhn, 6afk – PaTrmD + inhibitor

6wyq – PaTrmD + SAM

6wyr – PaTrmD + SFG

5zhj – MtTrmD + SAH

5zhk, 5zhl – MtTrm + inhibitor

5wt1 – PabTrm5a + tRNA + SAH

5hji – PabTrm5a + adenosine

5wt3 – PabTrm5a + tRNA + methylthioadenosine

7mys – AbTrmD + SAH

7kff – CdTrmD + SAH

tRNA guanine 46 N7 methyltransferase

2vdu, 2vdv – yTrm8

1yzh – Trm – Streptococcus pneumoniae

2fca, 7nzj – BsTrmB – Bacillus subtilis

3dxx – EcTrmB

Complexes of tRNA guanine 46 N7 methyltransferase

3ckk – hTrm + SAM - human

7pl1 – hTrm + sinefungin

7ogj – hTrm + SAH

3dxy – EcTrmB + SAM

3dxz – EcTrmB + SAH

7nyb – BsTrmD + SAM

7nzi – BsTrmD + SAH

Trm to O2 of guanosine 18

7edc – EcTrmH (mutant) + SAM

Trm to O2 of cytidine 32

4cnd – EcTrmJ (mutant)

4xbo – EcTrmJ + SAH

4cne – EcTrmJ (mutant) + SAH

METTL6 to cytidine 32

7f1e – hMETTL6 + SAM

7ezg – hMETTL6 + SAH

tRNA cytidine 34 O2 methyltransferase YibK

6jp6 – yTrm7

3e5y – BpTrmH – Burkholderia pseudomalllei

4jak, 4kdz – EcTrmL

7e3s – TrmL – Shewanella oneidensis<br />

7e3r – VvTrmL – Vibrio vulnificus

1j85, 6ahw, 7d51 – HiYibK

6qkv, 6qh8 – PaYibK

6ahw – HiTrm

Complexes of tRNA cytidine 34 O2 methyltransferase

6jpl – yTrm7 + SAM

4kgn – BpTrm + SAH

3n4k, 3n4j – Trm + SAH – Yersinia pestis

1mxi, 1im8 – HiTrm + SAH

4jal – EcYibK + SAH

7e3q – VvTrm + SAH

Trm to C5 of cytidine 38

6fdf – fyTrm + SAH

Trm to O2 of cytidine/uridine

5gra – TrmJ – Zymomonas mobilis

5gmc, 5gmb – PaTrmJ <b />

5gm8 – PaTrmJ + SFG

tRNA guanine 6 N2 methyltransferase

3tm5 – PfTrm14 + SFG – Pyrococcvus furiosus

3tlj – PfTrm14 + SAH

3tm4 – PfTrm14 + SAM

Trm to N2 of guanine 10

6zxy – AfTrm11 – Archaeoglobus fulgidus

6zxv, 6zxw – AfTrm11 + SFG

Trm M2G/M22G10

5e71 – TkTrm – Thermococcvus kodakarensis

5e72 – TkTrm + SAM

Trm to N1 of adenine 9

5a7t, 5a7z – SaTrm – Sulfolobus acidocaldarius

4cnf – SaTrm (mutant)

5a7y – SaTrm + SAH

4cng – SaTrm (mutant) + SAH

Trm to N1 of adenine 22

6q56 – BsTrm (mutant)

6qe6 – TrmK + SAH - Mycoplasma capricolum

7o4m – SaTrm

7o4o – SaTrm + SAH

7o4n – SaTrm + SAM

tRNA adenine 58 N1 methyltransferase

5ccb, 5cd1 – hTrm + SAH + tRNA-Lys

5ccx – hTrm + tRNA-Lys

5eqj – yTrm6

5erg – yTrm6 + SAM

2pwy – TtTrm – Thermus thermophilus

5c0o, 5c1i – TtTrm (mutant) + SAM

Trm to uracil 34

4qnx – EcTrm

4qnu, 4qnv – EcTrm + SAM derivative

Trm9-Trm112 to uracil 34

5cm2 – Trm – Yarrowia lipolytica

tRNA uracil 54 methyltransferase

3bt7 – yTrmA + RNA

Trm dual specificity Rlmn

4pl1, 4pl2 – EcTrm Rlmn (mutant) + SAM

5hr6, 5hr7 – EcTrm RlmN (mutant) + tRNA-Glu

Trm10 dual specificity to N1 of adenine 9/guanine 9

7onu – hTrm10 in RNase P complex – Cryo EM

6ems, 6emt – TkTrm10 (mutant)

6emv – TkTrm10 (mutant) + SAH

6emu – TkTrm10 (mutant) + SAM