Telomerase-associated protein

From Proteopedia

spinqualitylabelsall models Telomerase-associated protein p65 C-terminal complex with RNA and K+ ion (purple) (PDB code 4erd) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Contents 1 Function 2 Structural highlights Function The telomerase-associated proteins (TAP) are components of the ribonucleoprotein complex responsible for telomerase activity and catalyze the addition of new telomeres on the chromosome ends[1]. Structural highlights The [2].

3D structures of telomerase-associated protein

Updated on 14-December-2023

5dof, 5dfm - TtTAP 19 - Tetrahymena thermophyla
5doi - TtTAP 19 + TAP p45
5dok - TtTAP p45
5dfn - TtTAP p45 C-terminal
2lsl - TtTAP p65 C-terminal - NMR
4erd - TtTAP p65 C-terminal + RNA
4eyt - TtTAP p65 C-terminal
7x5c - TtTAP p50+p75 - NMR
3u4v, 3u4z, 3u50 - TtTAP p82 TEB1 domain
6d6v, 7lma, 7lmb - TtTAP in telomerase complex - Cryo EM

For telomerase-associated protein 2 see telomerase

References

1. ↑ Lewis KA, Wuttke DS. Telomerase and telomere-associated proteins: structural insights into mechanism and evolution. Structure. 2012 Jan 11;20(1):28-39. doi: 10.1016/j.str.2011.10.017. PMID:22244753 doi:http://dx.doi.org/10.1016/j.str.2011.10.017
2. ↑ Singh M, Wang Z, Koo BK, Patel A, Cascio D, Collins K, Feigon J. Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol Cell. 2012 Jun 14. PMID:22705372 doi:10.1016/j.molcel.2012.05.018