Twinfilin

From Proteopedia

3D structures of twinfilin

Updated on 12-June-2022

Domains: N-terminal ADF-H 1-142; C-terminal ADF-H 176-316

2vac – hTwi-2 N-terminal ADF-H domain - human
2w0i – hTwi-2 C-terminal ADF-H domain (mutant)
7ccc – hTwi-1 + F-actin-capping protein + actin
2hd7, 2d8b – mTwi-1 C-terminal ADF-H domain – mouse - NMR
1m4j – mTwi-1 N-terminal ADF-H domain
6rsw – mTwi-1 C-terminal ADF-H domain + actin + CAP1
7ds2 – mTwi-1 C-terminal + F-actin-capping protein
7ds4 – mTwi-1 C-terminal (mutant) + F-actin-capping protein
7dsb – mTwi-1 C-terminal + F-actin-capping protein + myotrophin
7ds3 – mTwi-2 + F-actin-capping protein
6yp9 – rTwi-1 C-terminal ADF-H domain + actin - rabbit
3daw – rTwi-1 C-terminal ADF-H domain (mutant) + actin + ATP
6k2f – Twi – Entamoeba histolytica

References

1. ↑ Palmgren S, Vartiainen M, Lappalainen P. Twinfilin, a molecular mailman for actin monomers. J Cell Sci. 2002 Mar 1;115(Pt 5):881-6. PMID:11870207
2. ↑ Li L, Liu L, Qu B, Li X, Gao X, Zhang M. Twinfilin 1 enhances milk bio-synthesis and proliferation of bovine mammary epithelial cells via the mTOR signaling pathway. Biochem Biophys Res Commun. 2017 Oct 21;492(3):289-294. doi:, 10.1016/j.bbrc.2017.08.130. Epub 2017 Aug 31. PMID:28864421 doi:http://dx.doi.org/10.1016/j.bbrc.2017.08.130
3. ↑ Paavilainen VO, Oksanen E, Goldman A, Lappalainen P. Structure of the actin-depolymerizing factor homology domain in complex with actin. J Cell Biol. 2008 Jul 14;182(1):51-9. PMID:18625842 doi:10.1083/jcb.200803100