Function
Uracil glycosylase inhibitor or uracil-DNA glycosylase inhibitor (UGI) is a small protein from Bacillus subtilis bacteriophage PBS1 which inhibits E. coli and other species’ uracil DNA glycosylase (UDG). UGI can disassociate UDG:DNA complexes[1].
Structural highlights
The [2] (Hydrophobic, Polar). Interacting UGI residues shown in ball-and-stick representation, UDG residues shown in spacefill representation.
3D structures of uracil glycosylase inhibitor
Updated on 07-January-2021
1ugi, 2ugi – UGI
1ugh – UGI + hUDG (mutant)
1uug, 1eui, 1lqg, 1lqm – UGI + EcUDG
2uug – UGI + EcUDG (mutant)
1udi – UGI + HsvUDG – Herpes simplex virus
2j8x - UGI + EBvUDG – Epstein-Barr virus
6lyd, 6lye - UGI + UDG – Bacillus phage PBS2
2zhx - UGI + MtUDG – Mycobacterium tuberculosis
4lyl – UDI + UDG – atlantic cod