Vacuolar protein sorting-associated protein 3D structures

From Proteopedia

3D structures of vacuolar protein sorting-associated protein

Updated on 17-March-2024- For a general description of the protein see Vacuolar protein sorting-associated protein

Vps4 domains: MIT 1-82; AAA ATPase 124-437

5xmi – yVps4 + ATP – yeast - Cryo EM

2rko – yVps4 AAA ATPase domain

3eie – yVps4 AAA ATPase domain (mutant)

3eih – yVps4 AAA ATPase domain (mutant) + ATPγS

2qp9 – yVps4 83-437

2qpa – yVps4 (mutant) 83-437 + ADP

2v6x – yVps4 MIT domain + yVps2 C-terminal

4niq, 5fvk – yVps4 MIT domain + yVfa1 MIM2 domain

5fvl – yVps4 MIT domain + yVPS20

3mhv – yVps4 + yVps Vta1

6ap1 – yVps4 + yVps Vta1 + peptide

6oo2, 6ndy – yVps4 + yVps Vta1 + peptide - Cryo EM

5uie – yVps4 + yVps2 + yVps Vta1 – Cryo EM

5xmk – yVps4 (mutant) + yVps Vta1 + ATP – Cryo EM

6bmf – yVps4 AAA ATPase domain + yVps2P – Cryo EM

CHMP1B

6tz9 – hCHMP1B – human – Cryo EM

Vps2-1 or CHMP2A

7zcg, 7zch – hVps2-1 + hVsp24 – Cryo EM

Vps4A

1yxr – hVps4A MIT domain – human - NMR

2jq9 – hVps4A MIT domain + CHMP1A peptide - NMR

2k3w – yVps4A MIT domain + CHMP6 peptide - NMR

Vps4B or Skd1

2jqh, 2cpt, 1wr0 – hVps4B MIT domain - NMR

1xwi – hVps4B C-terminal

4u7y – hVps4B MIT domain + IST1 peptide

2jqk – hVps4B MIT domain + CHMP2B

7l9x – hVps4B + inhibitor

2zam – mVps4B - mouse

2zao – mVps4B + ADP

2zan – mVps4B + ATP

Vps4P

6ap1 – yVps4P + Vta1 + peptide + ADP - Cryo EM

Vps5

6h7w – CtVps5 in retromer – Chaetomium thermophilum - Cryo EM

Vps9

1mn3 – yVps9 CUE domain 398-451

1p3q – yVps9 CUE domain + ubiquitin

Vps9A

4g01 – Vps9A + RABF2B – Arabidopsis thaliana

Vps11

7zu0 – hVps11 + Vps16 + Vps18 + Vps33 + Vps39 + Vps41 in HOPS tethering complex – Cryo EM

8cuk – yVps11 WD40 domain 1-350

Vps13

6cbc – CtVps13 N-terminal (mutant)

Vps15 or serine/threonine protein kinase Vps15

3gre – yVps15 WD repeat domain

Vps17

7x4o – yVps17

Vps18

4uuy – yVps18

Vps23

2f6m – yVps23 C-terminal (mutant) + yVps28 N-terminal

3r42 – yVps23 N-terminal (mutant) + yVps27 peptide

2caz – yVps23 + yVps28 N-terminal + SRN2

2f66 – yVps23 C-terminal + yVps28 N-terminal + SRN2

2p22 – yVps23 + yVps28 N-terminal + SRN2 + peptide

1uzx – yVps23 UEV domain 1-161 + ubiquitin

3r3q – yVps23 UEV domain

Vps24 or CHMP3

[[[2gd5]], [3frt]], 3frv – hVps24

6zh3 – yVps24 - Cryo EM

Vps25

3htu – hVps23 C-terminal WH2 domain + hVps20 first helix

Vps 26

2fau – hVps26

Vps 26A

7blo – hVps26A + hVps35 + nexin-3 + DMT1 peptide - Cryo EM

4p2a – mVps26A + sorting nexin-3

6vac – mVps26A + Vps29 + Vps35

7u6f – mVps26A + Vps29 + Vps35 – Cryo EM

6md5 – Vps26A – zebrafish

7blq – CtVps26 + Vps35 + nexin-3 +Kex2 – Chaetomium thermophilum – Cryo EM

5f0l, 5f0m, 5f0p – Vps26A + Vps35 + SNX3

Vps26B

3lh8, 2r51 – mVps26B

3lh9, 3lha – mVps26B (mutant)

Vps26C

8syn, 8syo – hVps26C + Vps29 + Vps35L – Cryo EM

Vps26-like

6h7w – CtVps26L + Vsp29 + Vsp35 - Cryo EM

Vps27

2pjw – yVps27 C-terminal + protein

6njg – yVps27 + polyubiquitin

Vps28

6vme – hVps28 in ESCRT-I complex

2g3k, 2j9v – yVps28 C-terminal

2j9u – yVps28 + yVps36

Vps29

7bln, 8sym – hVps29 + hVps35 - Cryo EM

8ese – hVps29 + hVps35 peptide

5wyh – hVps29 + interaptin

5osh, 5osi – hVps29 + hVps35 + interaptin

5gtu – hVps29 + TBC1D5

3psn, 3pso – mVps29

6vab – mVps29 + Vps35 – Cryo EM

6tl0 – mVps29 + VARP – NMR

2r17 – yVps29 + yVps35

5w8m – CtVps29

6xs5, 6xs7, 6xs8, 6xs9, 6xsa – CtVps29 + peptide

6h7w – CtVps29 + CtVps35 + CtVps26-like + CtVPS - Cryo EM

7blp, 7blr – CtVps29 + CtVps35 - Cryo EM

5xce, 5xch – EhVps29 – Entamoeba histolytica

5xcj, 5xck – EhVps29 (mutant)

Vps30

3vp7 – hVps30 C-terminal

Vps32 or Snf7 or CHMP5

4abm – hVps32-2 hairpin 23-97

5fd9 – hVps32

3uly, 3um0, 3um1, 3um2, 3um3 – hVps32-2 C terminal + BROX

5fd7, 5t8l, 5t8n – yVps32

Vps33

5bv1 – CtVps33 + CtVps16

5bv0 – CtVps33 + CtVps16 + NYV1 + SM protein

8dit – CtVps33 + CtVps16 + CtVsp18 – Cryo EM

Vps33A

4bx8 – hVps33A

4bx9 – hVps33A + hVps16 C-terminal + SNARE domain

Vps34

5dfz – yVps34 + yVps38 + yVps15 + yVps30 + nanobody

Vps35

5f0k – hVps35 N-terminal

5f0j – hVps35 + hVps26A + sorting nexin-3

5f0l, 5f0m, 5f0p – hVps35 + hVps26A + sorting nexin-3 + DMT-1

6vac – mVps35 + mVps26A + mVps29 - Cryo EM

Vps36

5kc2 – yVps36 + yVps15

2hth – hVps36 GLUE domain 1-138 + ubiquitin

2zme, 3cuq – hVps36 + hVps25 + SNF8

Vps37A

8e22 – hVps37A

Vps45

6xjl – CtVps45

6xmd, 6xm1 – CtVps45 + Tig2 Qa SNARE

Vps46

3ggz – yVps46 MIM motif 176-204 + IST1

Vps53

3ns4 – yVps53 C-terminal

Vps54

3n1b – yVps54 C-terminal

3n1e – mVps54 C-terminal

Vps60

2luh – yVps60 + yVps Vta1 - NMR

Vps64

6a8w – yVps64 FHA domain

Vps72

6gej, 6gen – yVps72 in nucleosome – Cryo EM

Vps72 homolog

5chl – Vps72 + histone H2A.Z – Drosophila melanogaster

5fug – hVps72 N-terminal + histone H2A.Z

Vps74

2zih, 2zii – yVps74

4tu3 – yVps74 + SAC1

Vps75

3c9b, 3c9d, 5agc – yVps75

3dm7 – yVps75 (mutant)

2zd7 – yVps75 + peptide

3q68, 3q66 – yVps75 + histone acetyltransferase

3q33 – yVps75 + histone acetyltransferase + histone H3 peptide

6o22 – yVps75 + histone acetyltransferase + histone H3 peptide + histone H4 peptide + ASF1 - NMR

3q35 – yVps75 + histone acetyltransferase + acetyl CoA

5yps – Vps75 (mutant) – Pneumocystis carinii

Vps Vta1 or Lip5

2lxl – hVps Vta1

4txp – hVps Vta1 N-terminal

2rkk – yVps Vta1 N-terminal

2rkl – yVps Vta1 C-terminal

5h7p – yVps Vta1 N-terminal + yVps46 D1-D2 domain - NMR

4u7e – hVps Vta1 N-terminal + IST1

2lxm – hVps Vta1 N-terminal + CHMP5

4txq – hVps Vta1 N-terminal + CHMP1B

4txr – hVps Vta1 N-terminal + CHMP1B + CHMP5