View source for 3sbl


==Crystal Structure of New Delhi Metal-beta-lactamase-1 from Klebsiella pneumoniae==
<StructureSection load='3sbl' size='340' side='right'caption='[[3sbl]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sbl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbl OCA], [https://pdbe.org/3sbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbl RCSB], [https://www.ebi.ac.uk/pdbsum/3sbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.

==See Also==
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Babnigg J]]
[[Category: Binkowski TA]]
[[Category: Jedrzejczak R]]
[[Category: Joachimiak A]]
[[Category: Kim Y]]
[[Category: Mire J]]
[[Category: Sacchettini J]]
[[Category: Tesar C]]