View source for 5qht


==PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000065a==
<StructureSection load='5qht' size='340' side='right'caption='[[5qht]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5qht]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QHT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GQY:2-methoxy-4-morpholin-4-yl-aniline'>GQY</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qht OCA], [https://pdbe.org/5qht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qht RCSB], [https://www.ebi.ac.uk/pdbsum/5qht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qht ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.

==See Also==
*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Brandao-Neto J]]
[[Category: Douangamath A]]
[[Category: Edwards A]]
[[Category: Elkins J]]
[[Category: Kessler B]]
[[Category: Knapp S]]
[[Category: Krojer T]]
[[Category: Schuler H]]
[[Category: Schuller M]]
[[Category: Talon R]]
[[Category: Zhang R]]
[[Category: Von Delft F]]