View source for 8ug8


==Mus musculus Otopetrin 2 (mOTOP2) in pH 7.0, intermediate state==
<StructureSection load='8ug8' size='340' side='right'caption='[[8ug8]], [[Resolution|resolution]] 3.79&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ug8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UG8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UG8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.79&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ug8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ug8 OCA], [https://pdbe.org/8ug8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ug8 RCSB], [https://www.ebi.ac.uk/pdbsum/8ug8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ug8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OTOP2_MOUSE OTOP2_MOUSE] Proton-selective ion channel open at neutral pH (PubMed:29371428, PubMed:35920807, PubMed:37053086). Actives at neutral and alkaline extracellular pH, likely participates in some alkali-related physiological activities (PubMed:35920807, PubMed:37053086).<ref>PMID:29371428</ref> <ref>PMID:35920807</ref> <ref>PMID:37053086</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Gan N]]
[[Category: Jiang Y]]