View source for 9itr


==Chloroflexus aurantiacus ATP synthase, state 3, focused refinement of FO and peripheral stalk==
<StructureSection load='9itr' size='340' side='right'caption='[[9itr]], [[Resolution|resolution]] 4.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9itr]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Chloroflexus_aurantiacus_J-10-fl Chloroflexus aurantiacus J-10-fl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ITR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ITR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9itr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9itr OCA], [https://pdbe.org/9itr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9itr RCSB], [https://www.ebi.ac.uk/pdbsum/9itr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9itr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ATPL_CHLAA ATPL_CHLAA] F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
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</StructureSection>
[[Category: Chloroflexus aurantiacus J-10-fl]]
[[Category: Large Structures]]
[[Category: Wu J]]
[[Category: Xu X]]
[[Category: Zhang X]]