View source for 9qlf


==Human myoferlin (1-1997) in complex with an MSP2N2 lipid nanodisc (25 mol% DOPS, 5 mol% PI(4,5)P2 and 5 mol% Cholesterol)==
<StructureSection load='9qlf' size='340' side='right'caption='[[9qlf]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9qlf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QLF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PSF:1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE'>PSF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qlf OCA], [https://pdbe.org/9qlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qlf RCSB], [https://www.ebi.ac.uk/pdbsum/9qlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qlf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYOF_HUMAN MYOF_HUMAN] Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity).
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cretu C]]
[[Category: Moser T]]