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[[Image:1xwd polyview3d.png|right|390px]] In the field of modern endocrinology, a [[Hormone|hormone]] is any substance, generated either externally or internally, that operates via a receptor at the cellular level, which conveys to to the cell a message to stop, start, or modulate a cellular process. {{TOC limit|limit=2}} ==Guide to Proteopedia Pages Concerning Hormones and their Receptors== {{#tree:id=HormoneTopic|openlevels=0| Articles in Proteopedia concerning [[Hormone]] include: <!--* [[Follicle-stimulating hormone]] --> * [[Hormones and their receptors]] * [[Steroid Hormones and their receptors]] * [[Signal transduction]] * [[Sex steroids]] * [[Steroids]] * [[Human Follicle-Stimulating Hormone Complexed with its Receptor]] * [[Estrogen receptor]] * [[Estrogen-related receptor]] * [[Androgen receptor|Androgen Receptor]] * [[Leucine-rich repeat|Leucine-rich repeat proteins]] * [[Human growth hormone]] * [[Vascular Endothelial Growth Factor]] * [[Vascular Endothelial Growth Factor Receptor]] * [[Receiver domain of sensor histidine kinase CKI1]] * [[Beta-2 Adrenergic Receptor]] * [[Journal:JBSD:2|Neurotensin]] * [[Neurotensin receptor]] * [[Glucagon]] * [[Glucagon receptor]] * [[Hormone sensitive lipase]] * [[Corticosteroid-binding globulin]] * [[Erythropoietin]] * [[Erythropoietin receptor]] * [[Thyroid hormone receptor]] }} <br /> To view automatically seeded indices concerning [[Hormone]], see: *[[:Category:Hormone|Hormone]] *[[:Category:Hormone receptor|Hormone Receptor]] *[[:Category:Steroid receptor|Steroid receptor]] *[[:Category:Steroid hormone receptor|Steroid hormone receptor]] <br /> ==Additional 3D Structures of Hormones and Hormone Receptors and Related Molecules== ===Adrenaline=== [[Image:7tm labeled.png|right|400px]] [[Beta-2 Adrenergic Receptor]]<br /> The human β2 adrenergic receptor bound to a [[hormone]] analog and G-protein ([[3sn6]]) is featured in an image on the right, and additional structures are on the [[Adrenergic receptor|Adrenergic receptor page]]. <br /> {{Template:GPCR3sn6}} ===Angiotensinogen=== [[Serpin]] ===Chorionic Gonadotropin=== [[1hrp]], [[1hcn]] - hCG – human<br /> [[1hd4]] - α-subunit of hCG <br /> [[1e9j]], [[1dz7]] - α-subunit of hCG - NMR<br /> [[1qfw]] - hCG + antibody<br /> === Estrogen receptor === [[Estrogen receptor]] ===Estrogen-related Receptor=== [[Estrogen-related receptor]] ===Androgen Receptor=== [[Androgen receptor|Nuclear Androgen Receptor]] ===Follicle-Stimulating Hormone=== [[Follicle-stimulating hormone]] ===PACAP/glucagon family of peptide hormones=== [[3n94]] - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure [[2jod]] and vice versa <br /> [[2jod]] - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular ===Glucocorticoid=== [[Glucocorticoid receptor]] ===Glucose-dependent Insulinotropic Polypeptide=== [[Glucose-dependent Insulinotropic Polypeptide Receptor]] ===Growth Hormone=== [[Human growth hormone]] is featured [[Human growth hormone|here]].<br /> ===Insulin=== [[Insulin]] ===Progesterone === [[1a28]] - hProgR steroid-binding domain + progesterone<br /> ==See Also== * [[Cancer]] * [[Membrane proteins]] * [[G protein-coupled receptor|G protein-coupled receptors]] * [[Nobel Prizes for 3D Molecular Structure]] * [[Highest impact structures]] of all time * [[Hormones and their receptors]] ==External Resources== * [http://www.ssfa-gphr.de/index.php Sequence-Structure-Function-Analysis of Glycoprotein Hormone Receptors] * [http://gris.ulb.ac.be/ GRIS: Glycoprotein-hormone Receptors Information System] * [http://www.ssfa-7tmr.de/ssfe/ The GPCR-SSFE Database: A Homology Model Resource for G-Protein Coupled Receptors] * The [http://www.rcsb.org/pdb/101/motm.do?momID=52 feature on Growth Hormone] by Shuchismita Dutta and David S. Goodsell for the April 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month]. * [http://proteomics.ucsd.edu/Software/NeuroPedia.html NeuroPedia, a neuropeptide database and spectral library] [[Category:Topic Page]] [[Category:Hormone]] [[Category:Hormones]] [[Category:Endocrine]] [[Category:Endocrinology]] [[Category:Signaling]] [[Category:Cystine-knot growth factor|Cystine-knot growth factor]] [[Category:Cyclic cystine knot|Cyclic cystine knot]] [[Category:Cystine knot superfamily|Cystine knot superfamily]] [[Category:Cystine knot motif|Cystine knot motif]]

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