3kpe

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===Solution structure of the respiratory syncytial virus (RSV)six-helix bundle complexed with TMC353121, a small-moleucule inhibitor of RSV===
===Solution structure of the respiratory syncytial virus (RSV)six-helix bundle complexed with TMC353121, a small-moleucule inhibitor of RSV===
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{{ABSTRACT_PUBMED_19966279}}
==About this Structure==
==About this Structure==
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[[Category: Virion]]
[[Category: Virion]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 23 09:44:29 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Dec 24 07:31:01 2009''

Revision as of 05:31, 24 December 2009

Image:3kpe.jpg

Template:STRUCTURE 3kpe

Solution structure of the respiratory syncytial virus (RSV)six-helix bundle complexed with TMC353121, a small-moleucule inhibitor of RSV

Template:ABSTRACT PUBMED 19966279

About this Structure

3KPE is a 2 chains structure of sequences from Human respiratory syncytial virus a2. Full crystallographic information is available from OCA.

Reference

  • Roymans D, De Bondt HL, Arnoult E, Geluykens P, Gevers T, Van Ginderen M, Verheyen N, Kim H, Willebrords R, Bonfanti JF, Bruinzeel W, Cummings MD, van Vlijmen H, Andries K. Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein. Proc Natl Acad Sci U S A. 2009 Dec 4. PMID:19966279

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