1pvs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1pvs.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1pvs.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1pvs| PDB=1pvs | SCENE= }}
{{STRUCTURE_1pvs| PDB=1pvs | SCENE= }}
-
'''3-methyladenine Glcosylase II(AlkA) Hypoxanthine complex'''
+
===3-methyladenine Glcosylase II(AlkA) Hypoxanthine complex===
-
==Overview==
+
<!--
-
Escherichia coli (E. coli) protein 3-methyladenine-DNA glycosylase II (AlkA) functions primarily by removing alkylation damage from duplex and single stranded DNA. A crystal structure of AlkA was refined to 2.0 A resolution. This structure in turn was used to refine an AlkA-hypoxanthine (substrate) complex structure to 2.4 A resolution. The complex structure shows hypoxanthine located in AlkA's active site stacked between residues W218 and Y239. The structural analysis of the AlkA and AlkA-hypoxanthine structures indicate that free hypoxanthine binding in the active site may inhibit glycosylase activity.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12009927}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12009927 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12009927}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Hypoxanthine]]
[[Category: Hypoxanthine]]
[[Category: Reaction-product complex]]
[[Category: Reaction-product complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:32:36 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:46:27 2008''

Revision as of 10:46, 27 July 2008

Image:1pvs.png

Template:STRUCTURE 1pvs

3-methyladenine Glcosylase II(AlkA) Hypoxanthine complex

Template:ABSTRACT PUBMED 12009927

About this Structure

1PVS is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

3-methyladenine-DNA glycosylase II: the crystal structure of an AlkA-hypoxanthine complex suggests the possibility of product inhibition., Teale M, Symersky J, DeLucas L, Bioconjug Chem. 2002 May-Jun;13(3):403-7. PMID:12009927

Page seeded by OCA on Sun Jul 27 13:46:27 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/1pvs"
Personal tools