2pyp

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[[Image:2pyp.jpg|left|200px]]
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{{STRUCTURE_2pyp| PDB=2pyp | SCENE= }}
{{STRUCTURE_2pyp| PDB=2pyp | SCENE= }}
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'''PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED'''
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===PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED===
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==Overview==
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The blue-light photoreceptor photoactive yellow protein (PYP) undergoes a self-contained light cycle. The atomic structure of the bleached signaling intermediate in the light cycle of PYP was determined by millisecond time-resolved, multiwavelength Laue crystallography and simultaneous optical spectroscopy. Light-induced trans-to-cis isomerization of the 4-hydroxycinnamyl chromophore and coupled protein rearrangements produce a new set of active-site hydrogen bonds. An arginine gateway opens, allowing solvent exposure and protonation of the chromophore's phenolic oxygen. Resulting changes in shape, hydrogen bonding, and electrostatic potential at the protein surface form a likely basis for signal transduction. The structural results suggest a general framework for the interpretation of protein photocycles.
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(as it appears on PubMed at http://www.pubmed.gov), where 9045611 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9045611}}
==About this Structure==
==About this Structure==
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[[Category: Light sensor for phototaxis]]
[[Category: Light sensor for phototaxis]]
[[Category: Photoreceptor]]
[[Category: Photoreceptor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:24:59 2008''

Revision as of 18:25, 27 July 2008

Image:2pyp.png

Template:STRUCTURE 2pyp

PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED

Template:ABSTRACT PUBMED 9045611

About this Structure

2PYP is a Single protein structure of sequence from Halorhodospira halophila. Full crystallographic information is available from OCA.

Reference

Structure of a protein photocycle intermediate by millisecond time-resolved crystallography., Genick UK, Borgstahl GE, Ng K, Ren Z, Pradervand C, Burke PM, Srajer V, Teng TY, Schildkamp W, McRee DE, Moffat K, Getzoff ED, Science. 1997 Mar 7;275(5305):1471-5. PMID:9045611

Page seeded by OCA on Sun Jul 27 21:24:59 2008

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