Structural highlights
Function
AC4CH_ECOLI Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C). Can also hydrolyze N(4)-acetyl-2'-deoxycytidine and N(4)-acetylcytosine with lower efficiency. Has weaker activity towards a wide range of structurally different N(4)-acylated cytosines and cytidines.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Stanislauskienė R, Laurynėnas A, Rutkienė R, Aučynaitė A, Tauraitė D, Meškienė R, Urbelienė N, Kaupinis A, Valius M, Kaliniene L, Meškys R. YqfB protein from Escherichia coli: an atypical amidohydrolase active towards N(4)-acylcytosine derivatives. Sci Rep. 2020 Jan 21;10(1):788. PMID:31964920 doi:10.1038/s41598-020-57664-w