4fsf
From Proteopedia
Crystal structure of Pseudomonas aeruginosa PBP3 complexed with compound 14
Structural highlights
FunctionPublication Abstract from PubMedNovel siderophore-linked monobactams with in vitro and in vivo anti-microbial activity against MDR Gram-negative pathogens are described. Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infections.,Mitton-Fry MJ, Arcari JT, Brown MF, Casavant JM, Finegan SM, Flanagan ME, Gao H, George DM, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Irvine R, Lall MS, Megan Lemmon M, Li C, Lin J, McCurdy SP, Mueller JP, Mullins L, Niosi M, Noe MC, Pattavina D, Penzien J, Plummer MS, Risley H, Schuff BP, Shanmugasundaram V, Starr JT, Sun J, Winton J, Young JA Bioorg Med Chem Lett. 2012 Sep 15;22(18):5989-94. Epub 2012 Jul 20. PMID:22892121[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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