CRISPR subtype I-C

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Cas2 (PDB code 5h1o)

References

  1. Ka D, Hong S, Jeong U, Jeong M, Suh N, Suh JY, Bae E. Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity. Struct Dyn. 2017 May 19;4(5):054701. doi: 10.1063/1.4984052. eCollection 2017, Sep. PMID:28612041 doi:http://dx.doi.org/10.1063/1.4984052
  2. Hochstrasser ML, Doudna JA. Cutting it close: CRISPR-associated endoribonuclease structure and function. Trends Biochem Sci. 2015 Jan;40(1):58-66. doi: 10.1016/j.tibs.2014.10.007. Epub, 2014 Nov 18. PMID:25468820 doi:http://dx.doi.org/10.1016/j.tibs.2014.10.007

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